岩沙海葵毒素

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岩沙海葵毒素
IUPAC名
(E,2S,3R,5R,8R,9S)-10-[(2R,3R,4R,5S,6R)-6-[(1S,2R,3S,4S,5R,11S)-12-[(1R,3S,5S,7R)-5-[(8S)-9-[(2R,3R,4R,5R,6S)-6-[(E,2S,3S,6S,9R,10R)-10-[(2S,4R,5S,6R)-6-[(2R,3R)-4-[(2R,3S,4R,5R,6S)-6-[(2S,3Z,5E,8R,9S,10R,12Z,17S,18R,19R,20R)-21-[(2R,3R,4R,5S,6R)-6-[(Z,3R,4R)-5-[(1S,3R,5R,7R)-7-[2-[(2R,3R,5S)-5-(aminomethyl)-3-hydroxy-tetrahydrofuran-2-yl]ethyl]-2,6-dioxabicyclo[3.2.1]octan-3-yl]-3,4-dihydroxy-pent-1-enyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]-2,8,9,10,17,18,19-heptahydroxy-20-methyl-14-methylene-henicosa-3,5,12-trienyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]-2,3-dihydroxy-butyl]-4,5-dihydroxy-tetrahydropyran-2-yl]-2,6,9,10-tetrahydroxy-3-methyl-dec-4-enyl]-3,4,5,6-tetrahydroxy-tetrahydropyran-2-yl]-8-hydroxy-nonyl]-1,3-dimethyl-6,8-dioxabicyclo[3.2.1]octan-7-yl]-1,2,3,4,5-pentahydroxy-11-methyl-dodecyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]-2,5,8,9-tetrahydroxy-N-[(E)-3-(3-hydroxypropylamino)-3-oxo-prop-1-enyl]-3,7-dimethyl-dec-6-enamide
識別
CAS號 77734-91-9
PubChem 11105289
ChemSpider 9280425
SMILES
InChI
InChIKey CWODDUGJZSCNGB-HQNRRURTBU
性質
化學式 C129H223N3O54
摩爾質量 2680.14 g·mol−1
危險性
主要危害 胸痛、哮喘樣呼吸困難、心動過速、血壓不穩、溶血。
若非註明,所有數據均出自一般條件(25 ℃,100 kPa)下。

岩沙海葵毒素[1]英語:Palytoxin,又稱沙群海葵毒素,或簡稱為海葵毒素)含有129個碳原子,64個手性中心。白色粉末,無固定熔點,加熱至300℃炭化。是一類從沙群海葵科岩沙海葵中提取的水溶性線性聚醚。作為一種毒素,其毒性主要表現為與鈉鉀泵結合以及抑制ATP合酶,有收縮血管以及升高血壓作用。它的毒性在非蛋白質毒素中僅次於刺尾魚毒素

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