跳至內容

骨髓源性巨噬細胞

維基百科,自由的百科全書
BMDM的提取與培養

骨髓源性巨噬細胞(英語:Bone marrow-derived macrophageBMDM)是指由科研實驗室哺乳動物骨髓細胞生成的巨噬細胞。骨髓細胞中存在未分化的巨噬細胞前體,可以通過加入巨噬細胞集落刺激因子(macrophage colony-stimulating factor,M-CSF;CSF1)來分化培養[1],M-CSF是一個細胞因子,誘導細胞分化。BMDM細胞常用於免疫學細胞生物學研究[2]

參考文獻

[編輯]
  1. ^ Weischenfeldt, Joachim; Porse, Bo. Bone Marrow-Derived Macrophages (BMM): Isolation and Applications. Cold Spring Harbor Protocols. 2008-12-01, 2008 (12): pdb.prot5080 [2018-05-25]. ISSN 1940-3402. PMID 21356739. doi:10.1101/pdb.prot5080. (原始內容存檔於2022-03-04) (英語). 
  2. ^ oshizawa, S., et al. "Legionella Pneumophila Evades Gamma Interferon-Mediated Growth Suppression through Interleukin-10 Induction in Bone Marrow-Derived Macrophages." Infection and Immunity 73.5 (2005): 2709-17.