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骨髓源性巨噬细胞

维基百科,自由的百科全书
BMDM的提取与培养

骨髓源性巨噬细胞(英语:Bone marrow-derived macrophageBMDM)是指由科研实验室哺乳动物骨髓细胞生成的巨噬细胞。骨髓细胞中存在未分化的巨噬细胞前体,可以通过加入巨噬细胞集落刺激因子(macrophage colony-stimulating factor,M-CSF;CSF1)来分化培养[1],M-CSF是一个细胞因子,诱导细胞分化。BMDM细胞常用于免疫学细胞生物学研究[2]

参考文献

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  1. ^ Weischenfeldt, Joachim; Porse, Bo. Bone Marrow-Derived Macrophages (BMM): Isolation and Applications. Cold Spring Harbor Protocols. 2008-12-01, 2008 (12): pdb.prot5080 [2018-05-25]. ISSN 1940-3402. PMID 21356739. doi:10.1101/pdb.prot5080. (原始内容存档于2022-03-04) (英语). 
  2. ^ oshizawa, S., et al. "Legionella Pneumophila Evades Gamma Interferon-Mediated Growth Suppression through Interleukin-10 Induction in Bone Marrow-Derived Macrophages." Infection and Immunity 73.5 (2005): 2709-17.