麦芽酚

“Maltol”的各地常用名称
“Maltol”的各地常用名称
中国大陆	麦芽酚
台湾	麦芽醇
港澳	麦芽酚

麦芽酚
	IUPAC名; 3-Hydroxy-2-methyl-4H-pyran-4-one; 3-羟基-2-甲基-4H-4-吡喃酮
别名	落叶松酸、巴拉酮
识别
CAS号	118-71-8
PubChem	8369
ChemSpider	8066
SMILES	O=C1C=COC(C)=C1O;
InChI	1/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3;
InChIKey	XPCTZQVDEJYUGT-UHFFFAOYAH
性质
化学式	C6H6O3
摩尔质量	126.11 g·mol−1
密度	1.348
熔点	161-162 °C（434-435 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

麦芽酚（英语：Maltol）是一种天然存在的有机化合物，主要用作香料。它存在于落叶松的树皮、松针和烤麦芽中，由此得名。它是一种可溶于热水、氯仿和其他极性溶剂的白色结晶粉末。由于麦芽酚具有棉花糖和焦糖的气味，其可赋予香水甜味。麦芽酚的甜味可增加新鲜出炉面包的香味，可在面包和蛋糕中用作增味剂（INS编号636）。

麦芽酚与相关的3-羟基-4-吡喃酮化合物（如麹酸）可与硬的金属离子，如Fe³⁺、Ga³⁺、Al³⁺、VO²⁺配位，^[1]因此可用于增加体内铝^[2]的摄取量，也用于增加镓^[3]和铁^[4]的口服生物利用度。它的食品添加剂 E编号为E636。

参见

参考资料

^ B. D. Liboiron, K. H. Thompson, G. R. Hanson, E. Lam, N. Aebischer, C. Orvig. New Insights into the Interactions of Serum Proteins with Bis(maltolato)oxovanadium(IV): Transport and Biotransformation of Insulin-Enhancing Vanadium Pharmaceuticals. J. Am. Chem. Soc. 2005, 127: 5104–5115. doi:10.1021/ja043944n.
^ N. Kaneko, H. Yasui, J. Takada, K. Suzuki, H. Sakurai. Orally administrated aluminum-maltolate complex enhances oxidative stress in the organs of mice. J. Inorg. Biochem. 2004, 98: 2022–2031. doi:10.1016/j.jinorgbio.2004.09.008.
^ L. R. Bernstein, T. Tanner, C. Godfrey, B. Noll. Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability. Metal Based Drugs. 2000, 7: 33–48. doi:10.1155/MBD.2000.33.
^ D.M. Reffitt, T.J. Burden, P.T. Seed, J. Wood J, R.P. Thompson, J.J. Powell. Assessment of iron absorption from ferric trimaltol. Ann. Clin. Biochem. 2000, 37: 457–66. doi:10.1258/0004563001899645.

[1] B. D. Liboiron, K. H. Thompson, G. R. Hanson, E. Lam, N. Aebischer, C. Orvig. New Insights into the Interactions of Serum Proteins with Bis(maltolato)oxovanadium(IV): Transport and Biotransformation of Insulin-Enhancing Vanadium Pharmaceuticals. J. Am. Chem. Soc. 2005, 127: 5104–5115. doi:10.1021/ja043944n.

[2] N. Kaneko, H. Yasui, J. Takada, K. Suzuki, H. Sakurai. Orally administrated aluminum-maltolate complex enhances oxidative stress in the organs of mice. J. Inorg. Biochem. 2004, 98: 2022–2031. doi:10.1016/j.jinorgbio.2004.09.008.

[3] L. R. Bernstein, T. Tanner, C. Godfrey, B. Noll. Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability. Metal Based Drugs. 2000, 7: 33–48. doi:10.1155/MBD.2000.33.

[4] D.M. Reffitt, T.J. Burden, P.T. Seed, J. Wood J, R.P. Thompson, J.J. Powell. Assessment of iron absorption from ferric trimaltol. Ann. Clin. Biochem. 2000, 37: 457–66. doi:10.1258/0004563001899645.

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