2,3-二氨基丙酸
外觀
l-2,3-二氨基丙酸 | |
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IUPAC名 3-Amino-L-alanine 3-氨基-L-丙氨酸 | |
系統名 (2S)-2,3-Diaminopropanoic acid | |
識別 | |
CAS號 | 4033-39-0 |
PubChem | 97328 |
ChemSpider | 87849 |
SMILES |
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ChEBI | 16303 |
KEGG | C03401 |
性質 | |
化學式 | C3H8N2O2 |
摩爾質量 | 104.11 g·mol−1 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
2,3-二氨基丙酸(Dpr)[1]是一種非蛋白胺基酸,出現於一些次級代謝產物,包括雙效菌素A[2]和結核放線菌素。[3]
生物合成
[編輯]2,3-二氨基丙酸根離子由絲氨酸的磷酸吡哆醛(PLP)介導胺化生成。
![](http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/Diaminosynthesis.png/400px-Diaminosynthesis.png)
參考文獻
[編輯]- ^ Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, et al. Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions. Proceedings of the National Academy of Sciences of the United States of America. August 2019, 116 (33): 16338–16346. PMC 6697887
. PMID 31358633. doi:10.1073/pnas.1904849116
.
- ^ Rogers EW, Molinski TF. Asymmetric synthesis of diastereomeric diaminoheptanetetraols. A proposal for the configuration of (+)-zwittermicin a. Organic Letters. February 2007, 9 (3): 437–40. PMC 2729442
. PMID 17249781. doi:10.1021/ol062804a.
- ^ Thomas MG, Chan YA, Ozanick SG. Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster. Antimicrobial Agents and Chemotherapy. September 2003, 47 (9): 2823–30. PMC 182626
. PMID 12936980. doi:10.1128/AAC.47.9.2823-2830.2003.