MUC7

  「幽灵人种」重定向至此。关于其他用法，请见「幽靈人種 (消歧义)」。

  「MUC7」重定向至此。关于the MUC-7 conference，请见「Message Understanding Conference」。

MUC7
識別號
别名	MUC7；, MG2, mucin 7, secreted
外部ID	OMIM：158375 HomoloGene：133350 GeneCards：MUC7
基因位置（人类） 染色体 4號染色體 基因座 4q13.3 起始 70,430,492 bp 终止 70,482,997 bp
RNA表达模式
查阅更多表达数据
基因本體 分子功能 • 血浆蛋白结合 細胞組分 • Golgi lumen • 細胞外區域 • 外排體 • 细胞膜 生物學過程 • O-glycan processing • stimulatory C-type lectin receptor signaling pathway • antimicrobial humoral immune response mediated by antimicrobial peptide Sources:Amigo / QuickGO
直系同源
物種	人類	小鼠
Entrez	4589	无数据
Ensembl	ENSG00000171195	无数据
UniProt	Q8TAX7	无数据
mRNA​序列	NM_152291 ​NM_001145006 ​NM_001145007	无数据
蛋白序列	NP_001138478 ​NP_001138479 ​NP_689504	无数据
基因位置​（UCSC）	Chr 4: 70.43 – 70.48 Mb	无数据
PubMed​查找		无数据
維基數據
檢視/編輯人類

MUC7是人類基因的一部分，負責編碼Mucin-7這一種蛋白质。在其他動物，MUC7基因只見於大多數的胎盤動物；但在有袋類物種的基因卻找不到。

Human variations

人s carry either a five or six 串联重复 version of the gene. In other primates, the number of repeats found is 4-5 for 大猩猩s, 5 for 黑猩猩s, 6-7 for 猩猩屬s, 8-10 for 獼猴, 10-11 for 狒狒屬s and 11-12 for 绿猴s.

Further reading

• Zalewska A, Zwierz K, Zółkowski K, Gindzieński A. Structure and biosynthesis of human salivary mucins. Acta Biochimica Polonica. 2002, 47 (4): 1067–79. PMID 11996097. doi:10.18388/abp.2000_3960 . 
• Bobek LA, Tsai H, Biesbrock AR, Levine MJ. Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7). The Journal of Biological Chemistry. September 1993, 268 (27): 20563–9. PMID 7690757. doi:10.1016/S0021-9258(20)80762-5 . 
• Troxler RF, Iontcheva I, Oppenheim FG, Nunes DP, Offner GD. Molecular characterization of a major high molecular weight mucin from human sublingual gland. Glycobiology. October 1997, 7 (7): 965–73. PMID 9363439. doi:10.1093/glycob/7.7.965 . 
• Prakobphol A, Thomsson KA, Hansson GC, Rosen SD, Singer MS, Phillips NJ, Medzihradszky KF, Burlingame AL, Leffler H, Fisher SJ. Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. Biochemistry. April 1998, 37 (14): 4916–27. PMID 9538010. doi:10.1021/bi972612a. 
• Kirkbride HJ, Bolscher JG, Nazmi K, Vinall LE, Nash MW, Moss FM, Mitchell DM, Swallow DM. Genetic polymorphism of MUC7: allele frequencies and association with asthma. European Journal of Human Genetics. May 2001, 9 (5): 347–54. PMID 11378823. doi:10.1038/sj.ejhg.5200642 . 
• Guo JM, Zhang Y, Cheng L, Iwasaki H, Wang H, Kubota T, Tachibana K, Narimatsu H. Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12. FEBS Letters. July 2002, 524 (1–3): 211–8. PMID 12135769. S2CID 84453381. doi:10.1016/S0014-5793(02)03007-7 . 
• Cheng L, Tachibana K, Zhang Y, Guo J, Kahori Tachibana K, Kameyama A, Wang H, Hiruma T, Iwasaki H, Togayachi A, Kudo T, Narimatsu H. Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10. FEBS Letters. November 2002, 531 (2): 115–21. PMID 12417297. S2CID 221288147. doi:10.1016/S0014-5793(02)03399-9 . 
• Banderas-Tarabay JA, Zacarías-D'Oleire IG, Garduño-Estrada R, Aceves-Luna E, González-Begné M. Electrophoretic analysis of whole saliva and prevalence of dental caries. A study in Mexican dental students. Archives of Medical Research. 2003, 33 (5): 499–505. PMID 12459324. doi:10.1016/S0188-4409(02)00395-8. 
• Wang H, Tachibana K, Zhang Y, Iwasaki H, Kameyama A, Cheng L, Guo J, Hiruma T, Togayachi A, Kudo T, Kikuchi N, Narimatsu H. Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14. Biochemical and Biophysical Research Communications. January 2003, 300 (3): 738–44. PMID 12507512. doi:10.1016/S0006-291X(02)02908-X. 
• Soares RV, Siqueira CC, Bruno LS, Oppenheim FG, Offner GD, Troxler RF. MG2 and lactoferrin form a heterotypic complex in salivary secretions. Journal of Dental Research. June 2003, 82 (6): 471–5. PMID 12766201. S2CID 23276142. doi:10.1177/154405910308200613. 
• Ge J, Catt DM, Gregory RL. Streptococcus mutans surface alpha-enolase binds salivary mucin MG2 and human plasminogen. Infection and Immunity. November 2004, 72 (11): 6748–52. PMC 523000 . PMID 15501816. doi:10.1128/IAI.72.11.6748-6752.2004. 
• Grys TE, Siegel MB, Lathem WW, Welch RA. The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells. Infection and Immunity. March 2005, 73 (3): 1295–303. PMC 1064933 . PMID 15731026. doi:10.1128/IAI.73.3.1295-1303.2005. 
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M. Towards a proteome-scale map of the human protein-protein interaction network. Nature. October 2005, 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. PMID 16189514. S2CID 4427026. doi:10.1038/nature04209. 
• Bruno LS, Li X, Wang L, Soares RV, Siqueira CC, Oppenheim FG, Troxler RF, Offner GD. Two-hybrid analysis of human salivary mucin MUC7 interactions. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. October 2005, 1746 (1): 65–72. PMID 16203048. doi:10.1016/j.bbamcr.2005.08.007 . 
• Li S, Intini G, Bobek LA. Modulation of MUC7 mucin expression by exogenous factors in airway cells in vitro and in vivo. American Journal of Respiratory Cell and Molecular Biology. July 2006, 35 (1): 95–102. PMC 2658701 . PMID 16514118. doi:10.1165/rcmb.2005-0305OC. 

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