2,6-二乙酰基吡啶

2,6-Diacetylpyridine
	IUPAC名; 1,1′-(Pyridine-2,6-diyl)di(ethan-1-one)
别名	1,1′-(Pyridine-2,6-diyl)diethanone; 1-(6-Acetylpyridin-2-yl)ethanone; DAP ; 2,6-Bisacetylpyridine
识别
CAS号	1129-30-2
PubChem	70790
ChemSpider	63955
SMILES	CC(=O)c1cccc(n1)C(=O)C;
性质
化学式	C9H9NO2
摩尔质量	163.17 g·mol−1
外观	白色晶体
密度	1.119 g/cm3
熔点	81 °C
沸点	126 °C; 110至130 °C（230至266 °F；383至403 K）（升华）
危险性
	GHS危险性符号;
GHS提示词	Warning
H-术语	H315, H319, H335
P-术语	P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405
相关物质
相关化合物	2-acetylpyridine
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

2,6-二乙酰基吡啶是一种有机化合物，化学式为C₉H₉NO₂。它可由以下两种方法制备：^[1]^[2]

它和盐酸羟胺在碱存在下反应，可以得到相应的肟（羟亚胺）；^[3]它和盐酸苯肼反应，可以得到相应的苯腙。^[4]它可以被硼氢化钠还原为α,α'-二甲基-2,6-吡啶二甲醇。^[5]

参考文献[编辑]

^ Yoshiro Ogata; Masaru Tsuchida; Akihiko Muramoto. Controlled Synthesis of 2-Acetyl-6-carbethioxypyridine and 2-6-Diacetylpyridine from 2,6-Dimethylpyridine. Synth. Commun. 2006, 35 (17): 2317–2324. S2CID 93168188. doi:10.1080/00397910500186995.
^ Schmidt, R.; Welch, M.B.; Palackal, S.J.; Alt, H.G. Hydrogenized iron(II) complexes as highly active ethene polymerization catalysts. Journal of Molecular Catalysis A: Chemical. 2001, 179 (1–2): 155–173. doi:10.1016/S1381-1169(01)00333-8.
^ Christer B. Aakeröy, Abhijeet S. Sinha. Synthesis of ketoximes via a solvent-assisted and robust mechanochemical pathway. RSC Advances. 2013, 3 (22): 8168 [2022-03-15]. ISSN 2046-2069. doi:10.1039/c3ra40585k （英语）.
^ L. H. Abdel-Rahman, A. M. Abu-Dief, F. M. Atlam, A. A. H. Abdel-Mawgoud, A. A. Alothman, A. M. Alsalme, A. Nafady. Chemical, physical, and biological properties of Pd(II), V(IV)O, and Ag(I) complexes of N 3 tridentate pyridine-based Schiff base ligand. Journal of Coordination Chemistry. 2020-12-01, 73 (23): 3150–3173 [2022-03-15]. ISSN 0095-8972. doi:10.1080/00958972.2020.1842378 （英语）.
^ Jun'ichi Uenishi, Sachiko Aburatani, Taro Takami. Stereocomplexity and Stereoselective Synthesis of Triamine Molecules Bearing Four Chiral Carbon Centers: Stereodifferentiated Preparation of All 10 Stereoisomers of 2,6-Bis[1-(1-phenylethylamino)ethyl]pyridines. The Journal of Organic Chemistry. 2007-01-01, 72 (1): 132–138 [2022-03-15]. ISSN 0022-3263. doi:10.1021/jo061729e. （原始内容存档于2022-03-15）（英语）.

[1] Yoshiro Ogata; Masaru Tsuchida; Akihiko Muramoto. Controlled Synthesis of 2-Acetyl-6-carbethioxypyridine and 2-6-Diacetylpyridine from 2,6-Dimethylpyridine. Synth. Commun. 2006, 35 (17): 2317–2324. S2CID 93168188. doi:10.1080/00397910500186995.

[2] Schmidt, R.; Welch, M.B.; Palackal, S.J.; Alt, H.G. Hydrogenized iron(II) complexes as highly active ethene polymerization catalysts. Journal of Molecular Catalysis A: Chemical. 2001, 179 (1–2): 155–173. doi:10.1016/S1381-1169(01)00333-8.

[3] Christer B. Aakeröy, Abhijeet S. Sinha. Synthesis of ketoximes via a solvent-assisted and robust mechanochemical pathway. RSC Advances. 2013, 3 (22): 8168 [2022-03-15]. ISSN 2046-2069. doi:10.1039/c3ra40585k （英语）.

[4] L. H. Abdel-Rahman, A. M. Abu-Dief, F. M. Atlam, A. A. H. Abdel-Mawgoud, A. A. Alothman, A. M. Alsalme, A. Nafady. Chemical, physical, and biological properties of Pd(II), V(IV)O, and Ag(I) complexes of N 3 tridentate pyridine-based Schiff base ligand. Journal of Coordination Chemistry. 2020-12-01, 73 (23): 3150–3173 [2022-03-15]. ISSN 0095-8972. doi:10.1080/00958972.2020.1842378 （英语）.

[5] Jun'ichi Uenishi, Sachiko Aburatani, Taro Takami. Stereocomplexity and Stereoselective Synthesis of Triamine Molecules Bearing Four Chiral Carbon Centers: Stereodifferentiated Preparation of All 10 Stereoisomers of 2,6-Bis[1-(1-phenylethylamino)ethyl]pyridines. The Journal of Organic Chemistry. 2007-01-01, 72 (1): 132–138 [2022-03-15]. ISSN 0022-3263. doi:10.1021/jo061729e. （原始内容存档于2022-03-15）（英语）.

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