BW-723C86

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BW-723C86
BW-723C86.svg
识别信息
CAS号160521-74-4  ✓
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
化学信息
化学式C16H18N2OS
摩尔质量286.39 g·mol−1
3D model (JSmol)
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BW-723C86是一种人工合成的带有噻吩官能团色胺衍生物,分子式C16H18N2OS,可作为5-HT2B受体激动剂[1],在动物实验中显示出有抗焦慮藥作用[2]并对在一些其它组织中5-HT2B受体的功能进行了研究。

参考文献[编辑]

  1. ^ Kennett GA, Bright F, Trail B, Baxter GS, Blackburn TP. Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety. British Journal of Pharmacology. April 1996, 117 (7): 1443–8. PMC 1909458可免费查阅. PMID 8730737. doi:10.1111/j.1476-5381.1996.tb15304.x. 
  2. ^ Kennett GA, Trail B, Bright F. Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated. Neuropharmacology. December 1998, 37 (12): 1603–10. PMID 9886683. S2CID 7310462. doi:10.1016/S0028-3908(98)00115-4.