Template:PBB/57591

Megakaryoblastic leukemia (translocation) 1 巨核细胞白血病（易位）1
Rendering based on PDB 2KVU.
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 2KVU, 2KW9
标识
代号	MKL1; BSAC; MAL; MRTF-A
扩展标识	遗传学：606078 鼠基因：2384495 同源基因：32487 GeneCards: MKL1 Gene
基因本体论描述 分子功能 · transcription regulatory region sequence-specific DNA binding · sequence-specific DNA binding transcription factor activity · transcription coactivator activity · actin binding · actin monomer binding · protein binding · leucine zipper domain binding 细胞成分 · nucleus · nucleolus · cytoplasm 生物过程 · transcription, DNA-templated · positive regulation of transcription via serum response element binding · negative regulation of cysteine-type endopeptidase activity involved in apoptotic process · positive regulation of transcription from RNA polymerase II promoter · smooth muscle cell differentiation · negative regulation of apoptotic signaling pathway Sources: Amigo / QuickGO
RNA表达模式
更多表达数据
直系同源体
物种	人类	小鼠
Entrez	57591	223701
Ensembl	ENSG00000196588	ENSMUSG00000042292
UniProt	Q969V6	Q8K4J6
mRNA序列	NM_001282660	NM_001082536
蛋白序列	NP_001269589	NP_001076005
基因位置	Chr 22: 40.81 – 41.03 Mb	Chr 15: 81.01 – 81.19 Mb
PubMed查询	[1]	[2]