吉法酯 AHFS /Drugs.com 国际药品名称 ATC码
(2E )-3,7-dimethylocta-2,6-dien-1-yl (4E ,8E )-5,9,13-trimethyltetradeca-4,8,12-trienoate
CAS号 51-77-4 Y PubChem CID ChemSpider UNII KEGG ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.000.111 化学式 C 27 H 44 O 2 摩尔质量 400.637 g/mol 3D模型(JSmol )
CC(C)=CCC/C(C)=C/CC/C(C)=C/CCC(=O)OC/C=C(C)/CCC=C(C)C
InChI=1S/C27H44O2/c1-22(2)12-8-14-24(5)16-10-17-25(6)18-11-19-27(28)29-21-20-26(7)15-9-13-23(3)4/h12-13,16,18,20H,8-11,14-15,17,19,21H2,1-7H3/b24-16+,25-18+,26-20+
N Key:ZPACYDRSPFRDHO-ROBAGEODSA-N
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吉法酯 (英语:Gefarnate ,或译为合欢香叶酯 )是一种用于治疗胃及十二指肠溃疡 的药物[ 1] ,也可用于治疗干眼症 [ 2] [ 3] 。
^ Ohta Y, Kobayashi T, Imai Y, Inui K, Yoshino J, Nakazawa S. Effect of gefarnate on acute gastric mucosal lesion progression in rats treated with compound 48/80, a mast cell degranulator, in comparison with that of teprenone . Biol. Pharm. Bull. August 2005, 28 (8): 1424–30 [2019-12-20 ] . PMID 16079487 . doi:10.1248/bpb.28.1424 . (原始内容存档 于2019-08-30).
^ Peral A, Domínguez-Godínez CO, Carracedo G, Pintor J. Therapeutic targets in dry eye syndrome. Drug News Perspect. April 2008, 21 (3): 166–76. PMID 18560615 .
^ Gipson IK, Hori Y, Argüeso P. Character of ocular surface mucins and their alteration in dry eye disease . Ocul Surf. April 2004, 2 (2): 131–48 [2019-12-20 ] . PMID 17216084 . doi:10.1016/s1542-0124(12)70149-0 . (原始内容 存档于2020-05-20).