跳转到内容

2-二苯甲基哌啶

维基百科,自由的百科全书
2-二苯甲基哌啶
临床资料
给药途径By mouth, nasal and sublingual
ATC码
  • 未分配
法律规范状态
法律规范
药物动力学数据
生物利用度>90%
药物代谢Liver
生物半衰期16-20 hours
识别信息
  • (RS)-2-benzhydrylpiperidine
CAS号519-74-4  checkY
5807-81-8(盐酸盐)
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.007.525 编辑维基数据链接
化学信息
化学式C18H21N
摩尔质量251.37 g·mol−1
3D模型(JSmol英语JSmol
手性Racemic mixture
  • C1(C(C2NCCCC2)C3=CC=CC=C3)=CC=CC=C1
  • InChI=1S/C18H21N/c1-3-9-15(10-4-1)18(16-11-5-2-6-12-16)17-13-7-8-14-19-17/h1-6,9-12,17-19H,7-8,13-14H2 checkY
  • Key:RWTNXJXZVGHMGI-UHFFFAOYSA-N checkY

2-二苯甲基哌啶(英语:2-⁠diphenylmethylpiperidineDesoxypipradrol,缩写2-DPMP)分子式C18H21N,是一种去甲肾上腺素-多巴胺再吸收抑制剂(NDRI)[1],1950年代由汽巴精化开发[2]

参考文献

[编辑]
  1. ^ Ferris RM, Tang FL. Comparison of the effects of the isomers of amphetamine, methylphenidate and deoxypipradrol on the uptake of l-[3H]norepinephrine and [3H]dopamine by synaptic vesicles from rat whole brain, striatum and hypothalamus. The Journal of Pharmacology and Experimental Therapeutics. September 1979, 210 (3): 422–8. PMID 39160. 
  2. ^ US Patent 2820038 - 2-Diphenyl-Methyl-Piperidine