16α-氰基孕酮：修订间差异

16α-氰基孕酮
	IUPAC名; 3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile
	系统名; (1S,2R,3as,3bS,7S,9aR,9bS,11aS)-1-Acetyl-7-hydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthrene-2-carbonitrile
识别
CAS号	1434-54-4
PubChem	15032
ChemSpider	14308
SMILES	CC(=O)[C@H]1[C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C#N;
InChI	1/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1;
InChIKey	VSBHRRMYCDQLJF-ZDNYCOCVBP
IUPHAR配体	2762
性质
化学式	C22H31NO2
摩尔质量	341.49 g/mol g·mol⁻¹
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

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2024年3月16日 (六) 01:58的版本

16α-氰基孕酮（英語：Pregnenolone 16α-carbonitrile，缩写为PCN）是一种含氮有机化合物，分子式C₂₂H₃₁NO₂，可作为毒蕈碱拮抗剂（英语：Muscarinic antagonist），是托特罗定（英语：Tolterodine）的羟基衍生物，也是其异丁酸酯弗斯特罗定（英语：Fesoterodine）的活性代謝產物。^[1]^[2]^[3]

参考文献

^ J.I. Mason. Genetics of Steroid Biosynthesis and Function. CRC Press. 2 September 2003: 449–. ISBN 978-0-203-30149-4.
^ Giacinto Bagetta; Marco Cosentino; Marie Tiziana Corasaniti; Shinobu Sakurada. Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health. CRC Press. 19 April 2016: 250–. ISBN 978-1-4398-3769-6.
^ Larisa Y. Poluektova; J. Victor Garcia-Martinez; Yoshio Koyanagi; Markus G. Manz; Andrew M. Tager. Humanized Mice for HIV Research. Springer. 18 February 2015: 350–. ISBN 978-1-4939-1655-9.

[Mason2003-1] J.I. Mason. Genetics of Steroid Biosynthesis and Function. CRC Press. 2 September 2003: 449–. ISBN 978-0-203-30149-4.

[BagettaCosentino2016-2] Giacinto Bagetta; Marco Cosentino; Marie Tiziana Corasaniti; Shinobu Sakurada. Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health. CRC Press. 19 April 2016: 250–. ISBN 978-1-4398-3769-6.

[PoluektovaGarcia-Martinez2015-3] Larisa Y. Poluektova; J. Victor Garcia-Martinez; Yoshio Koyanagi; Markus G. Manz; Andrew M. Tager. Humanized Mice for HIV Research. Springer. 18 February 2015: 350–. ISBN 978-1-4939-1655-9.

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[2]

[3]

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 }}
-'''{{PAGENAME}}'''（{{lang-en|Pregnenolone 16α-carbonitrile}}，缩写为'''PCN'''）是一种[[氮化合物|含氮]][[有机化合物]]，分子式[[C22H31NO2|C<sub>22</sub>H<sub>31</sub>NO<sub>2</sub>]]，可作为{{le|毒蕈碱拮抗剂|Muscarinic antagonist}}<ref>{{Cite web|url=http://www.freepatentsonline.com/y2012/0128773.html|title=Desfesoterodine in the Form of a Tartaric Acid Salt}}</ref>，是{{le|托特罗定|Tolterodine}}的[[羟基]]衍生物，也是其[[异丁酸]][[酯]]{{le|弗斯特罗定|Fesoterodine}}的[[活性代謝產物]]。
+'''{{PAGENAME}}'''（{{lang-en|Pregnenolone 16α-carbonitrile}}，缩写为'''PCN'''）是一种[[氮化合物|含氮]][[有机化合物]]，分子式[[C22H31NO2|C<sub>22</sub>H<sub>31</sub>NO<sub>2</sub>]]，可作为{{le|毒蕈碱拮抗剂|Muscarinic antagonist}}，是{{le|托特罗定|Tolterodine}}的[[羟基]]衍生物，也是其[[异丁酸]][[酯]]{{le|弗斯特罗定|Fesoterodine}}的[[活性代謝產物]]。<ref name="Mason2003">{{cite book|author=J.I. Mason|title=Genetics of Steroid Biosynthesis and Function|url=https://books.google.com/books?id=0B1oSWVN4SUC&pg=PA449|date=2 September 2003|publisher=CRC Press|isbn=978-0-203-30149-4|pages=449–}}</ref><ref name="BagettaCosentino2016">{{cite book|author1=Giacinto Bagetta|author2=Marco Cosentino|author3=Marie Tiziana Corasaniti |author4=Shinobu Sakurada |title=Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health|url=https://books.google.com/books?id=I2TRBQAAQBAJ&pg=PA250|date=19 April 2016|publisher=CRC Press|isbn=978-1-4398-3769-6|pages=250–}}</ref><ref name="PoluektovaGarcia-Martinez2015">{{cite book|author1=Larisa Y. Poluektova|author2=J. Victor Garcia-Martinez|author3=Yoshio Koyanagi |author4=Markus G. Manz |author5=Andrew M. Tager |title=Humanized Mice for HIV Research|url=https://books.google.com/books?id=EMy3BgAAQBAJ&pg=PA350|date=18 February 2015|publisher=Springer|isbn=978-1-4939-1655-9|pages=350–}}</ref>
 ==参考文献==