睾酮17β-脱氢酶 (NADP+)
| 睾酮17β-脱氢酶 (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| 识别码 | |||||||||
| EC編號 | 1.1.1.64 | ||||||||
| CAS号 | 9028-63-1 | ||||||||
| 数据库 | |||||||||
| IntEnz | IntEnz浏览 | ||||||||
| BRENDA | BRENDA入口 | ||||||||
| ExPASy | NiceZyme浏览 | ||||||||
| KEGG | KEGG入口 | ||||||||
| MetaCyc | 代谢路径 | ||||||||
| PRIAM | 概述 | ||||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 基因本体 | AmiGO / EGO | ||||||||
| |||||||||
睾酮17β-脱氢酶 (NADP+)（英語：testosterone 17β-dehydrogenase (NADP+)，EC 1.1.1.64 （页面存档备份，存于互联网档案馆））是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应：
睾酮17β-脱氢酶 (NADP+)主要参与雄激素和雌激素代谢过程。
参考文献
[编辑]- ENDAHL GL, KOCHAKIAN CD, HAMM D. Separation of a triphosphopyridine nucleotide-specific from a diphosphopyridine nucleotide-specific 17 beta-hydroxy-(testosterone) dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 2792–6. PMID 13696735.
- SWEAT ML, SAMUELS LT, LUMRY R. Preparation and characterization of the enzyme which converts testosterone to androstenedione. J. Biol. Chem. 1950, 185 (1): 75–84. PMID 15436478.
- Villee CA and Spencer JM. Some properties of the pyridine nucleotide-specific 17beta-hydroxy steroid dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 3615–3619. PMID 13781425.