5號染色體

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5號染色體
5號染色體
物種 Homo sapiens
基因數量 900-1300

人類的5號染色體是23對染色體的其中之一,正常狀況下每個細胞擁有兩條。此染色體含有大約181百萬個鹼基對,佔細胞內所有DNA將近6%。其中有900到1300個基因,依預測方式而有所不同。

参考文献[编辑]

  • Cornish K, Bramble D. Cri du chat syndrome: genotype-phenotype correlations and recommendations for clinical management. Dev Med Child Neurol. 2002, 44 (7): 494–7. PMID 12162388. 
  • Mainardi PC, Perfumo C, Cali A, Coucourde G, Pastore G, Cavani S, Zara F, Overhauser J, Pierluigi M, Bricarelli FD. Clinical and molecular characterisation of 80 patients with 5p deletion: genotype-phenotype correlation. J Med Genet. 2001, 38 (3): 151–8. PMID 11238681. 
  • Schafer IA, Robin NH, Posch JJ, Clark BA, Izumo S, Schwartz S. Distal 5q deletion syndrome: phenotypic correlations. Am J Med Genet. 2001, 103 (1): 63–8. PMID 11562936. 
  • Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM. The DNA sequence and comparative analysis of human chromosome 5. Nature en. 2004, 431 (7006): 268–74. PMID 15372022. 
  • Siddiqi R, Gilbert F. Chromosome 5. Genet Test. 2003, 7 (2): 169–87. PMID 12885343. 
  • Wu Q, Niebuhr E, Yang H, Hansen L. Determination of the 'critical region' for cat-like cry of Cri-du-chat syndrome and analysis of candidate genes by quantitative PCR en. Eur J Hum Genet. 2005, 13 (4): 475–85. PMID 15657623. 
  • Zhang X, Snijders A, Segraves R, Zhang X, Niebuhr A, Albertson D, Yang H, Gray J, Niebuhr E, Bolund L, Pinkel D. High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization. Am J Hum Genet. 2005, 76 (2): 312–26. PMID 15635506.