5号染色体

维基百科,自由的百科全书
跳到导航 跳到搜索
5号染色体
5号染色体
物种 Homo sapiens
基因数量 900-1300

人类的5号染色体是23对染色体的其中之一,正常状况下每个细胞拥有两条。此染色体含有大约181百万个碱基对,占细胞内所有DNA将近6%。其中有900到1300个基因,依预测方式而有所不同。

参考文献[编辑]

  • Cornish K, Bramble D. Cri du chat syndrome: genotype-phenotype correlations and recommendations for clinical management. Dev Med Child Neurol. 2002, 44 (7): 494–7. PMID 12162388. 
  • Mainardi PC, Perfumo C, Cali A, Coucourde G, Pastore G, Cavani S, Zara F, Overhauser J, Pierluigi M, Bricarelli FD. Clinical and molecular characterisation of 80 patients with 5p deletion: genotype-phenotype correlation. J Med Genet. 2001, 38 (3): 151–8. PMID 11238681. 
  • Schafer IA, Robin NH, Posch JJ, Clark BA, Izumo S, Schwartz S. Distal 5q deletion syndrome: phenotypic correlations. Am J Med Genet. 2001, 103 (1): 63–8. PMID 11562936. 
  • Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM. The DNA sequence and comparative analysis of human chromosome 5. Nature en. 2004, 431 (7006): 268–74. PMID 15372022. 
  • Siddiqi R, Gilbert F. Chromosome 5. Genet Test. 2003, 7 (2): 169–87. PMID 12885343. 
  • Wu Q, Niebuhr E, Yang H, Hansen L. Determination of the 'critical region' for cat-like cry of Cri-du-chat syndrome and analysis of candidate genes by quantitative PCR en. Eur J Hum Genet. 2005, 13 (4): 475–85. PMID 15657623. 
  • Zhang X, Snijders A, Segraves R, Zhang X, Niebuhr A, Albertson D, Yang H, Gray J, Niebuhr E, Bolund L, Pinkel D. High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization. Am J Hum Genet. 2005, 76 (2): 312–26. PMID 15635506. 

参见[编辑]