蘭氏結

蘭氏結
蘭氏結
	Drawing of a peripheral nerve axon (labeled "axis cylinder"), showing a node of Ranvier along with other features
	光学显微镜下的兰氏结
基本信息
系統	神经系统
位置	Myelinated axon of a nerve
标识字符
拉丁文	incisura myelini
MeSH	D011901
TH	H2.00.06.2.03015
	《显微解剖学术语（英语：Anatomical terms of microanatomy）》 [在维基数据上编辑]

蘭氏結（英語：Nodes of Ranvier）又名郎氏結，郎飞氏结。是神经元的一部分，以首位描述該結構的法國科學家路易斯·安托万·兰维尔為名^[1]。

神經元的髓鞘包覆著軸突，蘭氏結是神經元上每隔數毫米就會出現的沒有髓鞘的部分。

跳跃传导学说认为，因为在蘭氏结之间的结间区的电阻极高，而在结区的电阻极低，并且轴突膜仅在结区可接触细胞外液，所以，局部电流必须在蘭氏结处穿出膜在髓鞘处形成回路，进行跳跃式传导^[2]。

虾的内侧大纤维没有蘭氏结^[3]。

概論

典型神經元的結構

附加圖片

神經元細胞結構示意圖
Medullated nerve fibers stained with silver nitrate

參見

結間段（英语：Internodal segment）（節間段、結間體）
施旺細胞
少突神經膠質細胞（英语：Oligodendrocyt）（少突膠質細胞、寡突膠細胞、寡突細胞、少突細胞、稀少突起阿膠細胞、稀突起膠細胞）
髓磷脂

參考文獻

^ R. Douglas Fields，〈大腦白質有價值〉，《科學人》第74期2008年4月號，第44-54頁，2009-4-20查閱
^ 神经系统概述^{[永久失效連結]}
^ 周围神经损伤. [2007-07-01]. （原始内容存档于2007-09-27）.

參考文獻

Baumann, Nicole; Pham-Dinh, Danielle. Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System. Physiological Reviews. 2001, 81 (2): 871–927 [2007-07-13]. PMID 11274346. （原始内容存档于2007-05-26）.
Ragheb, Fadi. The M3 Muscarinic Acetylcholine Receptor Mediates p42^mapk Activation and c-fos mRNA Expression in Oligodendrocyte Progenitors (PDF). Ottawa: National Library of Canada. 1999 [2006-03-07]. （原始内容存档 (PDF)于2006-05-16）.
Raine, C.S. (1991). Oligodendrocytes and central nervous system myelin. In Textbook of Neuropathology, second edition, R.L. Davis and D.M. Robertson, eds. (Baltimore, Maryland: Williams and Wilkins), pp. 115–141.
Tkachev D, Mimmack ML, Ryan MM, et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet. September 2003, 362 (9386): 798–805. PMID 13678875. doi:10.1016/S0140-6736(03)14289-4.
Káradóttir, R.; D. Attwell. Neurotransmiter receptors in the life and death of oligodendrocytes. Neuroscience. 14 April 2007, 145 (4): 1426–1438. PMC 2173944 . PMID 17049173. doi:10.1016/j.neuroscience.2006.08.070.
Carlson, Neil. Physiology of Behavior. Boston, MA: Allyn & Bacon. 2010: 38–39. ISBN 0-205-66627-2.
Sokol, Stacey. The Physiology and Pathophysiology of Multiple Sclerosis. Multiple Sclerosis: Physiological Tutorial. [2012-04-29]. （原始内容存档于2012-07-16）.
Fields, Douglas. White Matter Matters. Scientific American. 18 February 2008, 298 (March 2008): 54–61 [2012-04-29]. Bibcode:2008SciAm.298c..54D. doi:10.1038/scientificamerican0308-54. （原始内容存档于2013-11-01）.
Menn, Benedicte; Oscar Gonzalez-Perez. Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain. The Journal of Neuroscience. 26 July 2006, 26 (30): 7907–7918 [2012-04-29]. PMID 16870736. doi:10.1523/JNEUROSCI.1299-06.2006. （原始内容存档于2019-12-07）.
Gonzalez-Perez, O, B; Romero-Rodriguez, R; Soriano-Navarro, M; Garcia-Verdugo, JM; Alvarez-Buylla, A. Epidermal growth factor induces the progeny of subventricular zone type B cells to migrate and differentiate into oligodendrocytes.. Stem Cells. 2009, 27 (8): 2032–43. PMC 3346259 . PMID 19544429. doi:10.1002/stem.119.
Vallstedt, A; Klos JM; Ericson F. Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron. 1. 6 January 2005, 45 (1): 55–67. PMID 15629702. doi:10.1016/j.neuron.2004.12.026.
Thomas, JL; Spassky N; Perez Villegas EM; Olivier C; Cobos I; Goujet-Zalc C; Martínez S; Zalc B. Spatiotemporal development of oligodendrocytes in the embryonic brain. Journal of Neuroscience Research. 15 February 2000, 59 (4): 471–476. PMID 10679785. doi:10.1002/(SICI)1097-4547(20000215)59:4<471::AID-JNR1>3.0.CO;2-3.
Richardson, WD; Kessaris, N; Pringle, N. Oligodendrocyte wars. Nature Reviews Neuroscience. 1. 2006, 7 (1): 11–18. PMID 16371946. doi:10.1038/nrn1826.

外部連結

Cell Centered Database – Node of Ranvier （页面存档备份，存于互联网档案馆）
Organology at UC Davis nervous/pns/nerve2/nerve5 – "PNS, nerve (LM, Medium)"

[SA-1] R. Douglas Fields，〈大腦白質有價值〉，《科學人》第74期2008年4月號，第44-54頁，2009-4-20查閱

[2] 神经系统概述^{[永久失效連結]}

[3] 周围神经损伤. [2007-07-01]. （原始内容存档于2007-09-27）.

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