1-萘异硫氰酸酯
| 1-萘异硫氰酸酯 | |
|---|---|
| |
| IUPAC名 1-Isothiocyanatonaphthalene[1] | |
| 别名 | 1-Naphthylisothiocyanate; α-Naphthyl isothiocyanate; Kesscocide |
| 识别 | |
| 缩写 | ANIT |
| CAS号 | 551-06-4 
|
| PubChem | 11080 |
| ChemSpider | 10609 |
| SMILES |
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| InChI |
|
| InChIKey | JBDOSUUXMYMWQH-UHFFFAOYAA |
| Beilstein | 637868 |
| UN编号 | 2811 |
| EINECS | 208-990-8 |
| ChEBI | 35455 |
| RTECS | NX9100000 |
| MeSH | 1-Naphthylisothiocyanate |
| 性质 | |
| 化学式 | C11H7NS |
| 摩尔质量 | 185.24 g·mol−1 |
| 外观 | 白色蜡状固体[2] |
| 熔点 | 57—58 °C（330—331 K）[2] |
| 沸点 | 190 °C（463 K）（20 mmHg）[2] |
| 危险性 | |
GHS危险性符号 
| |
| GHS提示词 | 危险 |
| H-术语 | H301, H312, H315, H319, H332, H334, H335 |
| P-术语 | P261, P280, P301+310, P305+351+338, P342+311 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
1-萘异硫氰酸酯（英语：1-Naphthyl isothiocyanate，缩写ANIT，或称为异硫氰酸1-萘酯）是一种有机化合物，分子式C11H17NS，可看作异硫氰酸与1-萘酚形成的酯。
合成
[编辑]它可由1-萘胺和二硫化碳（或硫光气[3]）在三乙胺存在下反应得到[4]，也可由α-萘硫脲和氯苯合成[5]。
参考文献
[编辑]- ^ CID 11080 from PubChem
- ^ 2.0 2.1 2.2 J. D. Kendall, H. G. Suggate. 319. The reactivity of the alkylthio-group in nitrogen ring compounds. Part I. A general method for the preparation of symmetrical and unsymmetrical thiacyanines. Journal of the Chemical Society (Resumed). 1949: 1503 [2023-03-22]. ISSN 0368-1769. doi:10.1039/jr9490001503 （英语）.
- ^ Hiroyuki Kai, Yasuhide Morioka, Minoru Tomida, Tadashi Takahashi, Maki Hattori, Kohji Hanasaki, Katsumi Koike, Hiroki Chiba, Shunji Shinohara, Toshiyuki Kanemasa, Yuka Iwamoto, Kohji Takahashi, Yoshitaka Yamaguchi, Takahiko Baba, Takayoshi Yoshikawa, Hideyuki Takenaka. 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds. Bioorganic & Medicinal Chemistry Letters. 2007-07, 17 (14): 3925–3929 [2023-03-22]. doi:10.1016/j.bmcl.2007.04.099. （原始内容存档于2022-11-22） （英语）.
- ^ Raphaël Lebeuf, Isabelle Férézou, Jean Rossier, Stellios Arseniyadis, Janine Cossy. Straightforward Synthesis of the Near-Infrared Fluorescent Voltage-Sensitive Dye RH1691 and Analogues Thereof. Organic Letters. 2009-11-05, 11 (21): 4822–4825 [2023-03-22]. ISSN 1523-7060. doi:10.1021/ol901846g. （原始内容存档于2023-03-25） （英语）.
- ^ a-NAPHTHYL ISOTHIOCYANATE. Organic Syntheses. 1956, 36: 56. doi:10.15227/orgsyn.036.0056.