L-木酮糖还原酶
外观
L-木酮糖还原酶 | |||||||||
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人源木酮糖还原酶全酶(PDB 1pr9) | |||||||||
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识别码 | |||||||||
EC编号 | 1.1.1.10 | ||||||||
CAS号 | 9028-17-5 | ||||||||
数据库 | |||||||||
IntEnz | IntEnz浏览 | ||||||||
BRENDA | BRENDA入口 | ||||||||
ExPASy | NiceZyme浏览 | ||||||||
KEGG | KEGG入口 | ||||||||
MetaCyc | 代谢路径 | ||||||||
PRIAM | 概述 | ||||||||
PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
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L-木酮糖还原酶(英语:L-xylulose reductase,EC 1.1.1.10 (页面存档备份,存于互联网档案馆))是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应:
良性L-木酮糖还原酶缺乏可导致戊糖尿病。
参考文献
[编辑]- Doten, R.C. and Mortlock, R.P. Characterization of xylitol-utilizing mutants of Erwinia uredovora.. J. Bacteriol. 1985, 161: 529–533. PMID 2981816 (英语).
- Hickman, J. and Ashwell, G. A. sensitive and stereospecific enzymatic assay for xylulose.. J. Biol. Chem. 1959, 234: 758–761 (英语).
- Hollmann, S. and Touster, O. The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria.. J. Biol. Chem. 1957, 225: 87–102 (英语).
- Touster, O., Reynolds, V.H. and Hutcheson, R.M. The reduction of L-xylulose to xylitol by guinea pig liver mitochondria.. J. Biol. Chem. 1956, 221: 697–709 (英语).