| 曲喹辛
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IUPAC名
9,10-Dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one
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| 識別
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| CAS號
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79855-88-2  Y
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| PubChem
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5537
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| ChemSpider
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5336
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| SMILES
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- CC1=CC(=C(C(=C1)C)N=C2C=C3C4=CC(=C(C=C4CCN3C(=O)N2C)OC)OC)C
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| InChI
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- 1S/C24H27N3O3/c1-14-9-15(2)23(16(3)10-14)25-22-13-19-18-12-21(30-6)20(29-5)11-17(18)7-8-27(19)24(28)26(22)4/h9-13H,7-8H2,1-6H3
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| InChIKey
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MCMSJVMUSBZUCN-UHFFFAOYSA-N
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| 性質
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| 化學式
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C24H27N3O3
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| 摩爾質量
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405.49 g·mol−1
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| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。
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曲喹辛（英語：Trequinsin，也譯為「曲林菌素」）是一種含氮有機化合物，分子式C24H27N3O3，可作為磷酸二酯酶抑制藥[1]，在體外實驗（in vitro）中能增強精子活性[2]。
參考文獻[編輯]
- ^ Whitaker, RM; Wills, LP; Stallons, LJ; Schnellmann, RG. CGMP-Selective Phosphodiesterase Inhibitors Stimulate Mitochondrial Biogenesis and Promote Recovery from Acute Kidney Injury. The Journal of Pharmacology and Experimental Therapeutics. 2013, 347 (3): 626–34. PMC 3836317
. PMID 24042162. doi:10.1124/jpet.113.208017.
- ^ McBrinn, RC; Fraser, J; Hope, AG; Gray, DW; Barratt, CLR; Martins da Silva, SJ; Brown, SG. Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function.. British journal of pharmacology. 2019-12, 176 (23): 4521–4536. PMID 31368510. doi:10.1111/bph.14814.
