丁酰辅酶A脱氢酶

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Short-chain acyl-CoA dehydrogenase
2vig.jpg
Short-chain acyl-CoA dehydrogenase tetramer, Human
识别码
EC编号 1.3.8.1
CAS号 9027-88-7
数据库
IntEnz IntEnz浏览
BRENDA英语BRENDA BRENDA入口
ExPASy英语ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc英语MetaCyc 代谢路径
PRIAM英语PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBj PDBe PDBsum

短链酰基-CoA脱氢酶(又称丁酰-CoA脱氢酶丁酰-CoA脱氢酶丁酰脱氢酶不饱和酰基-CoA还原酶乙烯还原酶烯酰 - 辅酶A还原酶不饱和酰基辅酶A还原酶丁酰辅酶A脱氢酶短链酰基辅酶A脱氢酶短链酰基辅酶A脱氢酶)是一种是一种具有系统名称的短链酰基-CoA:电子转移黄素蛋白2,3-氧化还原酶[1][2][3][4][5][6]。该酶催化下列化学反应

短链酰基-CoA +电子传递黄素蛋白短链反式-2,3-脱氢酰基-CoA+脱电子传递黄素蛋白

这种酶含有FAD作为辅酶

参考[编辑]

  1. ^ Mahler, H. R. Studies on the fatty acid oxidizing system of animal tissues. IV. The prosthetic group of butyryl coenzyme A dehydrogenase. The Journal of Biological Chemistry. 1954-1, 206 (1): 13–26. ISSN 0021-9258. PMID 13130522. 
  2. ^ Green, D. E.; Mii, S.; Mahler, H. R.; Bock, R. M. Studies on the fatty acid oxidizing system of animal tissues. III. Butyryl coenzyme A dehydrogenase. The Journal of Biological Chemistry. 1954-1, 206 (1): 1–12. ISSN 0021-9258. PMID 13130521. 
  3. ^ Shaw, L.; Engel, P. C. The purification and properties of ox liver short-chain acyl-CoA dehydrogenase. The Biochemical Journal. 1984-03-01, 218 (2): 511–520. ISSN 0264-6021. PMC 1153367. PMID 6712627. 
  4. ^ Thorpe, C.; Kim, J. J. Structure and mechanism of action of the acyl-CoA dehydrogenases. FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 1995-6, 9 (9): 718–725. ISSN 0892-6638. PMID 7601336. 
  5. ^ Ikeda, Y.; Okamura-Ikeda, K.; Tanaka, K. Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme. The Journal of Biological Chemistry. 1985-01-25, 260 (2): 1311–1325. ISSN 0021-9258. PMID 3968063. 
  6. ^ McMahon, Brian; Gallagher, Mary E.; Mayhew, Stephen G. The protein coded by the PP2216 gene of Pseudomonas putida KT2440 is an acyl-CoA dehydrogenase that oxidises only short-chain aliphatic substrates. FEMS microbiology letters. 2005-09-01, 250 (1): 121–127. ISSN 0378-1097. PMID 16024185. doi:10.1016/j.femsle.2005.06.049.