前扣带皮层

维基百科,自由的百科全书
跳到导航 跳到搜索
前扣带皮层
MRI anterior cingulate.png
前扣带皮层(黄色标记处)
Gray727-Brodman.png
前扣带皮层位于布罗德曼分区系统第24、32、33分区
细节
识别标示
拉丁文Cortex cingularis anterior
NeuroNames英语NeuroNames161
NeuroLex英语NeuroLex IDbirnlex_936
神经解剖学术语英语Anatomical terms of neuroanatomy

前扣带皮层(英文:Anterior cingulate cortex),在人脑中,是大脑扣带皮层的前部,包围了胼胝体的前部[1]。前扣带皮层属于布罗德曼分区系统第24、25、32、33分区[1]。前扣带皮层参与了许多脑部的高阶功能,包括注意力分配[2]、奖励、决策[3]道德伦理[4]、冲动控制(譬如错误检测与纠正[5]、情感[6][7]等。

结构[编辑]

在解剖学上,前扣带皮层位于后扣带皮层前部,可分为背部(认知区)、前部(情感区)[8]。背部常被称为“中扣带皮层(midcingulate cortex)”,与前额叶皮质顶叶运动系统等区域相连,使其成为“自上而下和自下而上刺激”的核心站[1][9]。前部则与杏仁核伏隔核下丘脑丘脑、前岛叶等相连,参与评估情感显化和激励性信息[9]

特别的是,前扣带皮层含有纺锤体神经元(仅在人类及其它灵长类动物大象鲸豚类动物上发现),与脑部处理困难问题的功能有关[10][11]

功能[编辑]

许多研究认为,前扣带皮层参与了错误检测与纠正、任务预期、激励、注意力、情感调控等功能[2][3][4][5][6][7]。在压力环境下,前扣带皮层可能还参与调节自主神经系统,譬如调节血压和心率[12]

临床[编辑]

前扣带皮层异常可能与强迫症、情绪不稳、无法认知错误、无动性缄默症英语Akinetic mutism社交焦虑等病症有关[8][13][14]

图像[编辑]

参见[编辑]

参考资料[编辑]

  1. ^ 1.0 1.1 1.2 Jumah, Fareed R.; Dossani, Rimal H. Neuroanatomy, Cingulate Cortex. StatPearls. Treasure Island (FL): StatPearls Publishing. 2021. PMID 30725762. 
  2. ^ 2.0 2.1 Pardo JV, Pardo PJ, Janer KW, Raichle ME. The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm. Proceedings of the National Academy of Sciences of the United States of America. January 1990, 87 (1): 256–9. Bibcode:1990PNAS...87..256P. PMC 53241可免费查阅. PMID 2296583. doi:10.1073/pnas.87.1.256. 
  3. ^ 3.0 3.1 Bush G, Vogt BA, Holmes J, Dale AM, Greve D, Jenike MA, Rosen BR. Dorsal anterior cingulate cortex: a role in reward-based decision making. Proceedings of the National Academy of Sciences of the United States of America. January 2002, 99 (1): 523–8. Bibcode:2002PNAS...99..523B. PMC 117593可免费查阅. PMID 11756669. doi:10.1073/pnas.012470999. 
  4. ^ 4.0 4.1 Sevinc G, Gurvit H, Spreng RN. Salience network engagement with the detection of morally laden information. Social Cognitive and Affective Neuroscience. July 2017, 12 (7): 1118–1127. PMC 5490682可免费查阅. PMID 28338944. doi:10.1093/scan/nsx035. 
  5. ^ 5.0 5.1 Golchert, Johannes; Smallwood, Jonathan; Jefferies, Elizabeth; Liem, Franziskus; Huntenburg, Julia M.; Falkiewicz, Marcel; Lauckner, Mark E.; Oligschläger, Sabine; Villringer, Arno. In need of constraint: Understanding the role of the cingulate cortex in the impulsive mind. NeuroImage. 2017-02-01, 146: 804–813. ISSN 1095-9572. PMID 27989844. doi:10.1016/j.neuroimage.2016.10.041. 
  6. ^ 6.0 6.1 Decety J, Jackson PL. The functional architecture of human empathy. Behavioral and Cognitive Neuroscience Reviews. June 2004, 3 (2): 71–100. PMID 15537986. doi:10.1177/1534582304267187. 
  7. ^ 7.0 7.1 Jackson, Philip L.; Brunet, Eric; Meltzoff, Andrew N.; Decety, Jean. Empathy examined through the neural mechanisms involved in imagining how I feel versus how you feel pain. Neuropsychologia. 2006, 44 (5): 752–761. ISSN 0028-3932. PMID 16140345. doi:10.1016/j.neuropsychologia.2005.07.015. 
  8. ^ 8.0 8.1 Bush, George; Luu, Phan; Posner, Michael I.; Bush, George; Luu, Phan; Posner, Michael I.; Bush, George; Luu, Phan; Posner, Michael I. Cognitive and emotional influences in anterior cingulate cortex. Trends in Cognitive Sciences. 2000-06-01, 4 (6): 215–222. ISSN 1364-6613. PMID 10827444. doi:10.1016/S1364-6613(00)01483-2 (英语). 
  9. ^ 9.0 9.1 Posner MI, DiGirolamo GJ. Executive attention: Conflict, target detection, and cognitive control. Parasuraman R (编). The attentive brain. Cambridge, Mass: MIT Press. 1998. ISBN 0-262-16172-9. 
  10. ^ Brain Cells for Socializing. Smithsonian Magazine. [2021-04-04] (英语). 
  11. ^ Allman JM, Hakeem A, Erwin JM, Nimchinsky E, Hof P. The anterior cingulate cortex. The evolution of an interface between emotion and cognition. Annals of the New York Academy of Sciences. May 2001, 935: 107–17. Bibcode:2001NYASA.935..107A. PMID 11411161. doi:10.1111/j.1749-6632.2001.tb03476.x. 
  12. ^ Gianaros, Peter J.; Derbyshire, Stuart W. G.; May, J. Christopher; Siegle, Greg J.; Gamalo, Mark A.; Jennings, J. Richard. Anterior cingulate activity correlates with blood pressure during stress. Psychophysiology. 2005-11, 42 (6): 627–635. ISSN 0048-5772. PMC 2246096可免费查阅. PMID 16364058. doi:10.1111/j.1469-8986.2005.00366.x. 
  13. ^ McGovern, Robert A.; Sheth, Sameer A. Role of the dorsal anterior cingulate cortex in obsessive-compulsive disorder: converging evidence from cognitive neuroscience and psychiatric neurosurgery. Journal of Neurosurgery. 2017-01, 126 (1): 132–147. ISSN 1933-0693. PMID 27035167. doi:10.3171/2016.1.JNS15601. 
  14. ^ Lieberman, Matthew D.; Eisenberger, Naomi I. Pains and Pleasures of Social Life. Science. 2009-02-13, 323 (5916): 890–891. ISSN 0036-8075. PMID 19213907. doi:10.1126/science.1170008 (英语).