TAS2R46

味觉感受器，类型2，成员46
味觉感受器，类型2，成员46
标识
代号	TAS2R46; T2R46; T2R54
扩展标识	遗传学：612774 鼠基因：2681256 同源基因：131216 IUPHAR: GeneCards: TAS2R46 Gene
基因本体论描述
分子功能	· G-protein coupled receptor activity;
细胞成分	· integral to membrane; · cilium membrane;
生物过程	· sensory perception of taste;
	Sources: Amigo / QuickGO
直系同源体
物种	人类
Entrez	259292
Ensembl	ENSG00000226761
UniProt	P59540
mRNA序列	NM_176887
蛋白序列	NP_795368
基因位置	Chr 12:; 11.21 – 11.21 Mb
PubMed查询	[1]
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味觉感受器，类型2，成员46，TAS2R46 是一个人类基因组中TAS2R46基因编码的蛋白质，是苦味味觉感受器的一员。^[1]^[2]

另见

^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W. The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet. Oct 2002, 32 (3): 397–401. PMID 12379855. doi:10.1038/ng1014.
^ Entrez Gene: TAS2R46 taste receptor, type 2, member 46.

Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction.. J. Biol. Chem. 2002, 277 (1): 1–4. PMID 11696554. doi:10.1074/jbc.R100054200.
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Conte C, Ebeling M, Marcuz A; et al. Identification and characterization of human taste receptor genes belonging to the TAS2R family.. Cytogenet. Genome Res. 2003, 98 (1): 45–53. PMID 12584440. doi:10.1159/000068546.
Fischer A, Gilad Y, Man O, Pääbo S. Evolution of bitter taste receptors in humans and apes.. Mol. Biol. Evol. 2005, 22 (3): 432–6. PMID 15496549. doi:10.1093/molbev/msi027.
Go Y, Satta Y, Takenaka O, Takahata N. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.. Genetics. 2006, 170 (1): 313–26. PMC 1449719 . PMID 15744053. doi:10.1534/genetics.104.037523.