CCL1

CCL1（英語：Chemokine (C-C motif) ligand 1）是一小分子的细胞因子属于CC趋化因子家族，是由活化的T细胞分泌的糖蛋白^[1]。CCL1与细胞表面的趋化因子受体CCR8结合^[2]。CCL1对单核细胞，自然杀伤细胞，未成熟的B细胞和树突状细胞有细胞趋化作用^[1]。人类的CCL1基因与许多CC趋化因子的基因相邻聚集在第17染色体上^[3].

参见[编辑]

^ ^1.0 ^1.1 Miller MD, Krangel MS. The human cytokine I-309 is a monocyte chemoattractant. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2950-4.
^ Roos RS, Loetscher M, Legler DF, Clark-Lewis I, Baggiolini M, Moser B. Identification of CCR8, the receptor for the human CC chemokine I-309. J Biol Chem. 1997 Jul 11;272(28):17251-4.
^ Miller MD, Wilson SD, Dorf ME, Seuanez HN, O'Brien SJ, Krangel MS. Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines. J Immunol. 1990 Oct 15;145(8):2737-44.