2-丁基咪唑

2-丁基咪唑
英文名	2-butylimidazole
別名	2-正丁基咪唑
識別
CAS號	50790-93-7
PubChem	11815351
性質
化學式	C7H12N2
摩爾質量	124.18 g·mol−1
外觀	晶體粉末
密度	0.979±0.06 g·cm−3（20 °C）
熔點	52 °C
沸點	294 °C
溶解性（水）	2 g（25 °C）
pKa	14.42±0.10（25 °C）
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

2-丁基咪唑是一種有機化合物，化學式為C₇H₁₂N₂。它可由1-(二乙氧基甲基)咪唑的鋰鹽和1-碘丁烷反應得到，產物分別用鹽酸、碳酸氫鈉處理後用三氯甲烷萃取提純。^[3]2-丁基-4,5-二氫咪唑的氧化反應也能得到2-丁基咪唑。^[4]它和碘在碳酸鈉的存在下於二氧六環中反應，可以得到2-丁基-4,5-二碘咪唑。^[5]它可以和鋅形成金屬有機框架材料。^[6]

參考文獻[編輯]

^ ^1.0 ^1.1 ^1.2 2-Butylimidazole 97.0+%, TCI America(TM). fisher scientific. [2021-09-15]. （原始內容存檔於2021-09-15）.
^ ^2.0 ^2.1 ^2.2 Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 ((C) 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-09-15].
^ N. J. Curtis, R. S. Brown. An easily introduced and removed protecting group for imidazole nitrogen: a convenient route to 2-substituted imidazoles. The Journal of Organic Chemistry. 1980-09, 45 (20): 4038–4040 [2021-09-15]. ISSN 0022-3263. doi:10.1021/jo01308a019. （原始內容存檔於2021-09-15）（英語）.
^ Mohammad Abdollahi-Alibeik, Iraj Mohammadpoor-Baltork, Mohammad Ali Zolfigol. Alumina supported potassium permanganate: an efficient reagent for chemoselective dehydrogenation of 2-imidazolines under mild conditions. Bioorganic & Medicinal Chemistry Letters. 2004-12, 14 (24): 6079–6082 [2021-09-15]. doi:10.1016/j.bmcl.2004.09.070 （英語）.
^ Steven J. Wittenberger, Andrew Tasker, Bryan K. Sorensen, B. Gregory Donner. 2-Butyl-4-iodoimidazole-5-carboxaldehyde: A Versatile Intermediate for the Synthesis of Highly Functionalized Imidazoles. Synthetic Communications. 1993-12, 23 (22): 3231–3248 [2021-09-15]. ISSN 0039-7911. doi:10.1080/00397919308011184 （英語）.
^ Hatem M. Titi, Mihails Arhangelskis, Athanassios D. Katsenis, Cristina Mottillo, Ghada Ayoub, Jean-Louis Do, Athena M. Fidelli, Robin D. Rogers, Tomislav Friščić. Metal–Organic Frameworks as Fuels for Advanced Applications: Evaluating and Modifying the Combustion Energy of Popular MOFs. Chemistry of Materials. 2019-07-09, 31 (13): 4882–4888 [2021-09-15]. ISSN 0897-4756. doi:10.1021/acs.chemmater.9b01488. （原始內容存檔於2022-01-06）（英語）.

[fish-1] 1.0 ^1.1 ^1.2 2-Butylimidazole 97.0+%, TCI America(TM). fisher scientific. [2021-09-15]. （原始內容存檔於2021-09-15）.

[ACD-2] 2.0 ^2.1 ^2.2 Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 ((C) 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-09-15].

[curtis-3] N. J. Curtis, R. S. Brown. An easily introduced and removed protecting group for imidazole nitrogen: a convenient route to 2-substituted imidazoles. The Journal of Organic Chemistry. 1980-09, 45 (20): 4038–4040 [2021-09-15]. ISSN 0022-3263. doi:10.1021/jo01308a019. （原始內容存檔於2021-09-15）（英語）.

[4] Mohammad Abdollahi-Alibeik, Iraj Mohammadpoor-Baltork, Mohammad Ali Zolfigol. Alumina supported potassium permanganate: an efficient reagent for chemoselective dehydrogenation of 2-imidazolines under mild conditions. Bioorganic & Medicinal Chemistry Letters. 2004-12, 14 (24): 6079–6082 [2021-09-15]. doi:10.1016/j.bmcl.2004.09.070 （英語）.

[5] Steven J. Wittenberger, Andrew Tasker, Bryan K. Sorensen, B. Gregory Donner. 2-Butyl-4-iodoimidazole-5-carboxaldehyde: A Versatile Intermediate for the Synthesis of Highly Functionalized Imidazoles. Synthetic Communications. 1993-12, 23 (22): 3231–3248 [2021-09-15]. ISSN 0039-7911. doi:10.1080/00397919308011184 （英語）.

[6] Hatem M. Titi, Mihails Arhangelskis, Athanassios D. Katsenis, Cristina Mottillo, Ghada Ayoub, Jean-Louis Do, Athena M. Fidelli, Robin D. Rogers, Tomislav Friščić. Metal–Organic Frameworks as Fuels for Advanced Applications: Evaluating and Modifying the Combustion Energy of Popular MOFs. Chemistry of Materials. 2019-07-09, 31 (13): 4882–4888 [2021-09-15]. ISSN 0897-4756. doi:10.1021/acs.chemmater.9b01488. （原始內容存檔於2022-01-06）（英語）.

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