本页使用了标题或全文手工转换

GRIA1

维基百科,自由的百科全书
跳到导航 跳到搜索
GRIA1
識別號
别名 GRIA1;GLUH1、​GLUR1、​GLURA、​GluA1、​Glutamate receptor, ionotropic, AMPA 1、​HBGR1、​glutamate ionotropic receptor AMPA type subunit 1
外部ID MGI95808 HomoloGene20226 GeneCardsGRIA1
相關疾病
肥胖症[1]
為以下藥物的標靶
ampa、​aniracetam、​cx516、​cx-546、​環噻嗪、​IDRA-21、​piracetam、​S-18986、​ly-300168、​gyki-2466、​NBQX、​tezampanel anhydrous、​argiotoxin、​Joro toxin[2]
直系同源
物種 人類 小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_000827、NM_001114183、NM_001258019、NM_001258020、NM_001258021、NM_001258022、NM_001258023、NR_047578、XM_017009392、XM_017009393

NM_001113325、NM_001252403、NM_008165、XM_006532234、XR_388348、XM_017314275

蛋白序列

NP_000818、NP_001107655、NP_001244948、NP_001244949、NP_001244950、NP_001244951、NP_001244952、XP_016864881、XP_016864882

NP_001106796、NP_001239332、NP_032191、XP_006532297、XP_017169764

基因位置​(UCSC) Chr 5: 153.49 – 153.81 Mb n/a
PubMed​查找 [3] [4]
維基數據
檢視/編輯 人類 檢視/編輯 小鼠

GRIA1(英语:glutamate receptor, ionotropic, AMPA 1)是由GRIA1 基因編碼的蛋白质[5][6]

交互作用[编辑]

GRIA1與以下蛋白質有交互作用:

參見[编辑]

參考[编辑]

  1. ^ 與GRIA1相關的疾病;在維基數據上查看/編輯參考. 
  2. ^ 對Glutamate ionotropic receptor AMPA type subunit 1起作用的藥物;在維基數據上查看/編輯參考. 
  3. ^ Human PubMed Reference:. 
  4. ^ Mouse PubMed Reference:. 
  5. ^ Puckett C, Gomez CM, Korenberg JR, Tung H, Meier TJ, Chen XN, Hood L. Molecular cloning and chromosomal localization of one of the human glutamate receptor genes. Proc Natl Acad Sci U S A. October 1991, 88 (17): 7557–61. PMC 52340. PMID 1652753. doi:10.1073/pnas.88.17.7557. 
  6. ^ McNamara JO, Eubanks JH, McPherson JD, Wasmuth JJ, Evans GA, Heinemann SF. Chromosomal localization of human glutamate receptor genes. J Neurosci. July 1992, 12 (7): 2555–62. PMID 1319477. 
  7. ^ Gardoni F, Mauceri D, Fiorentini C, Bellone C, Missale C, Cattabeni F, Di Luca M. CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction. J. Biol. Chem. November 2003, 278 (45): 44745–52. PMID 12933808. doi:10.1074/jbc.M303576200. 
  8. ^ Leonard AS, Davare MA, Horne MC, Garner CC, Hell JW. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J. Biol. Chem. July 1998, 273 (31): 19518–24. PMID 9677374. doi:10.1074/jbc.273.31.19518. 
  9. ^ Sans N, Racca C, Petralia RS, Wang YX, McCallum J, Wenthold RJ. Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway. J. Neurosci. October 2001, 21 (19): 7506–16. PMID 11567040. 
  10. ^ Shen L, Liang F, Walensky LD, Huganir RL. Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association. J. Neurosci. November 2000, 20 (21): 7932–40. PMID 11050113. 
  11. ^ Kohda K, Kamiya Y, Matsuda S, Kato K, Umemori H, Yuzaki M. Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors. Brain Res. Mol. Brain Res. January 2003, 110 (1): 27–37. PMID 12573530. doi:10.1016/s0169-328x(02)00561-2. 

深入閱讀[编辑]

外部連結[编辑]


GRIA1引用了美国国家医学图书馆提供的資料,这些資料属于公共领域