奈伐庫單抗

奈伐庫單抗（INN：Nesvacumab），或譯奈伐蘇單抗、耐斯伐庫單抗，是一種實驗性單克隆抗體，最初設計用於治療癌症。它的靶標是血管生成素2（英語：Angiopoietin 2）。^[1]^[2]截至2017年5月，該藥物正處於治療糖尿病性黃斑水腫的II期臨床試驗中。^[3]^[4]該藥物由再生元製藥公司開發。

參考資料[編輯]

^ Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab, American Medical Association.
^ Hussain RM, Neiweem AE, Kansara V, Harris A, Ciulla TA. Tie-2/Angiopoietin pathway modulation as a therapeutic strategy for retinal disease. Expert Opinion on Investigational Drugs. October 2019, 28 (10): 861–869. PMID 31513439. doi:10.1080/13543784.2019.1667333.
^ Clinical trial number NCT02713204 for "Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)" at ClinicalTrials.gov
^ Clinical trial number NCT02712008 for "Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)" at ClinicalTrials.gov