钝叶醇

钝叶醇
识别
CAS号	16910-32-0
PubChem	5047
ChemSpider	167937
SMILES	C[C@@H]1[C@H](CC[C@]2(C1CCC3=C2CC[C@]4([C@]3(CC[C@@H]4[C@H](C)CCC(=C)C(C)C)C)C)C)O;
InChI	1S/C30H50O/c1-19(2)20(3)9-10-21(4)23-13-17-30(8)26-12-11-24-22(5)27(31)15-16-28(24,6)25(26)14-18-29(23,30)7/h19,21-24,27,31H,3,9-18H2,1-2,4-8H3/t21-,22+,23-,24?,27+,28+,29-,30+/m1/s1;
InChIKey	MMNYKQIDRZNIKT-YLANKJTKSA-N
3DMet	B01524
ChEBI	17791
KEGG	C01943
性质
化学式	C30H50O
摩尔质量	426.72 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

钝叶醇（英语：Obtusifoliol，也译为钝叶甾醇，或称作4α,14α-二甲基-5α-麦角甾-8,24(28)-二烯-3β-醇，4α,14α-Dimethyl-5α-ergosta-8,24(28)-dien-3β-ol，分子式C₃₀H₅₀O）是真菌甾体代谢的一种中间产物，由ERG11（CYP51F1）14α-脱甲基化为Delta8,14-Sterol，再转化为4α-甲基粪生甾醇，最后生成麦角固醇^[1]。

参考文献

^ Park, HG; Lee, IS; Chun, YJ; Yun, CH; Johnston, JB; Montellano, PR; Kim, D. Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans.. Archives of biochemistry and biophysics. 1 May 2011, 509 (1): 9–15. PMID 21315684. doi:10.1016/j.abb.2011.02.002.

[1] Park, HG; Lee, IS; Chun, YJ; Yun, CH; Johnston, JB; Montellano, PR; Kim, D. Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans.. Archives of biochemistry and biophysics. 1 May 2011, 509 (1): 9–15. PMID 21315684. doi:10.1016/j.abb.2011.02.002.

[1]