TAS2R45

味觉感受器，类型2，成员45
味觉感受器，类型2，成员45
标识
代号	TAS2R45; GPR59; T2R45; ZG24P
扩展标识	遗传学：613967 GeneCards: TAS2R45 Gene
基因本体论描述
分子功能	· G-protein coupled receptor activity;
细胞成分	· integral to membrane;
生物过程	· sensory perception of taste;
	Sources: Amigo / QuickGO
直系同源体
物种	人类
Entrez	259291
Ensembl	ENSG00000256436
UniProt	P59539
mRNA序列	NM_176886
蛋白序列	NP_795367
基因位置	Chr 12:; 11.18 – 11.18 Mb
PubMed查询	[1]
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味觉感受器，类型2，成员45，TAS2R45 是一个人类基因组中TAS2R45基因编码的蛋白质，是苦味味觉感受器的一员。^[1]^[2]

另见

^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W. The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet. Oct 2002, 32 (3): 397–401. PMID 12379855. doi:10.1038/ng1014.
^ Entrez Gene: TAS2R45 taste receptor, type 2, member 45.

Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction.. J. Biol. Chem. 2002, 277 (1): 1–4. PMID 11696554. doi:10.1074/jbc.R100054200.
Montmayeur JP, Matsunami H. Receptors for bitter and sweet taste.. Curr. Opin. Neurobiol. 2002, 12 (4): 366–71. PMID 12139982. doi:10.1016/S0959-4388(02)00345-8.
Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Zhang Y, Hoon MA, Chandrashekar J; et al. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.. Cell. 2003, 112 (3): 293–301. PMID 12581520. doi:10.1016/S0092-8674(03)00071-0.
Go Y, Satta Y, Takenaka O, Takahata N. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.. Genetics. 2006, 170 (1): 313–26. PMC 1449719 . PMID 15744053. doi:10.1534/genetics.104.037523.