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8-溴茶鹼

維基百科,自由的百科全書
8-溴茶鹼
臨床資料
其他名稱溴茶鹼
識別資訊
  • 8-Bromo-1,3-dimethyl-7H-purine-2,6-dione
CAS號10381-75-6
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.030.757 編輯維基數據鏈接
化學資訊
化學式C7H7BrN4O2
摩爾質量259.06 g·mol−1
3D模型(JSmol英語JSmol
  • CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Br
  • InChI=1S/C7H7BrN4O2/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h1-2H3,(H,9,10)
  • Key:SKTFQHRVFFOHTQ-UHFFFAOYSA-N

8-溴茶鹼英語:8-Bromotheophylline)或8-溴-1,3-二甲基黃嘌呤,是一種黃嘌呤利尿藥。它是帕馬溴中的主要活性成分,它作為非處方藥撲熱息痛鎮痛藥一起出售,用於治療痛經[1][2]它也是一種腺苷A1受體拮抗劑[3]

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參考資料

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  1. ^ Ortiz MI, Murguía-Cánovas G, Vargas-López LC, Silva R, González-de la Parra M. Naproxen, paracetamol and pamabrom versus paracetamol, pyrilamine and pamabrom in primary dysmenorrhea: a randomized, double-blind clinical trial. Medwave. October 2016, 16 (9): e6587. PMID 27813503. doi:10.5867/medwave.2016.09.6587可免費查閱. 
  2. ^ Ortiz MI. Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment. European Journal of Obstetrics, Gynecology, and Reproductive Biology. September 2010, 152 (1): 73–77. PMID 20478651. doi:10.1016/j.ejogrb.2010.04.015. 
  3. ^ Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, et al. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. Journal of Medicinal Chemistry. September 1993, 36 (18): 2639–2644. PMID 8410976. doi:10.1021/jm00070a007.