TAS2R46

味覺感受器，類型2，成員46
味覺感受器，類型2，成員46
標識
代號	TAS2R46; T2R46; T2R54
擴展標識	遺傳學：612774 鼠基因：2681256 同源基因：131216 IUPHAR: GeneCards: TAS2R46 Gene
基因本體論描述
分子功能	· G-protein coupled receptor activity;
細胞成分	· integral to membrane; · cilium membrane;
生物過程	· sensory perception of taste;
	Sources: Amigo / QuickGO
直系同源體
物種	人類
Entrez	259292
Ensembl	ENSG00000226761
UniProt	P59540
mRNA序列	NM_176887
蛋白序列	NP_795368
基因位置	Chr 12:; 11.21 – 11.21 Mb
PubMed查詢	[1]
	閱; 論; 編;

味覺感受器，類型2，成員46，TAS2R46 是一個人類基因組中TAS2R46基因編碼的蛋白質，是苦味味覺感受器的一員。^[1]^[2]

另見

^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W. The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet. Oct 2002, 32 (3): 397–401. PMID 12379855. doi:10.1038/ng1014.
^ Entrez Gene: TAS2R46 taste receptor, type 2, member 46.

Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction.. J. Biol. Chem. 2002, 277 (1): 1–4. PMID 11696554. doi:10.1074/jbc.R100054200.
Montmayeur JP, Matsunami H. Receptors for bitter and sweet taste.. Curr. Opin. Neurobiol. 2002, 12 (4): 366–71. PMID 12139982. doi:10.1016/S0959-4388(02)00345-8.
Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Zhang Y, Hoon MA, Chandrashekar J; et al. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.. Cell. 2003, 112 (3): 293–301. PMID 12581520. doi:10.1016/S0092-8674(03)00071-0.
Conte C, Ebeling M, Marcuz A; et al. Identification and characterization of human taste receptor genes belonging to the TAS2R family.. Cytogenet. Genome Res. 2003, 98 (1): 45–53. PMID 12584440. doi:10.1159/000068546.
Fischer A, Gilad Y, Man O, Pääbo S. Evolution of bitter taste receptors in humans and apes.. Mol. Biol. Evol. 2005, 22 (3): 432–6. PMID 15496549. doi:10.1093/molbev/msi027.
Go Y, Satta Y, Takenaka O, Takahata N. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.. Genetics. 2006, 170 (1): 313–26. PMC 1449719 . PMID 15744053. doi:10.1534/genetics.104.037523.