再摄取强化剂

维基百科,自由的百科全书
跳转至: 导航搜索
Coluracetam英语Coluracetam,一種高親和力膽鹼攝取(HACU)增強劑。

再攝取強化劑 (Reuptake Enhancer , RE),有時也稱作再攝取激活劑,是一種再攝取調節劑英语reuptake modulator。可以增強膜上轉運蛋白神經遞質再攝取英语reuptake,使胞外神經遞質浓度下降,進而導致較少的神經傳導英语neurotransmission

一些再攝取增強劑:

Coluracetam英语Coluracetam是一種膽鹼再攝取強化劑[1]黄酮类木犀草素以及它的一些衍生物可增強多巴胺轉運體的再攝取作用[2][3]Caulis Sinomenii 的萃取物可增加DA/NE的再攝取[4]

参见[编辑]

参考资料[编辑]

  1. ^ MKC-231, a choline-uptake enhancer: long-lasting cognitive improvement after repeated administration in AF64A-treated rats., Pubmed.
  2. ^ Zhao G, Qin GW, Wang J, Chu WJ, Guo LH. Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt. Neurochem. Int. 2010, 56 (1): 168–76. PMID 19815045. doi:10.1016/j.neuint.2009.09.015. 
  3. ^ Zhang J, Liu X, Lei X, 等. Discovery and synthesis of novel luteolin derivatives as DAT agonists. Bioorg. Med. Chem. 2010, 18 (22): 7842–8. PMID 20971650. doi:10.1016/j.bmc.2010.09.049. 
  4. ^ Zhao G, Bi C, Qin GW, Guo LH. Caulis Sinomenii extracts activate DA/NE transporter and inhibit 5HT transporter. Exp. Biol. Med. (Maywood). 2009, 234 (8): 976–85. PMID 19491370. doi:10.3181/0903-RM-92.