VIS1 （英语：viral integration site 1 的缩写，也称为HIS-1 ）是一个长链非编码RNA 基因 [ 2] [ 3] 脊椎动物 中普遍存在[ 4] 上皮组织 中表达，和白血病 等癌 症的预后 有关[ 5]
^ Human PubMed Reference: . National Center for Biotechnology Information, U.S. National Library of Medicine. ^ Askew DS, Bartholomew C, Buchberg AM, et al. His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia . Oncogene. November 1991, 6 (11): 2041–2047. PMID 1682866 ^ Askew DS, Li J, Ihle JN. Retroviral insertions in the murine His-1 locus activate the expression of a novel RNA that lacks an extensive open reading frame . Mol. Cell. Biol. March 1994, 14 (3): 1743–1751. PMC 358532 PMID 8114708 doi:10.1128/MCB.14.3.1743 ^ Li J, Rhodes JC, Askew DS. Evolutionary conservation of putative functional domains in the human homolog of the murine His-1 gene. Gene. January 1997, 184 (2): 169–176. PMID 9031624 doi:10.1016/S0378-1119(96)00591-4 ^ Li J, Witte DP, Van Dyke T, Askew DS. Expression of the putative proto-oncogene His-1 in normal and neoplastic tissues . Am. J. Pathol. April 1997, 150 (4): 1297–1305. PMC 1858164 PMID 9094986
. PMID 8114708. doi:10.1128/MCB.14.3.1743.
