乙酰克里定

乙酰克里定
临床资料
AHFS/Drugs.com	国际药品名称
给药途径	Topical (ophthalmic solution)
ATC码	S01EB08 (WHO) ;
法律规范状态
法律规范	处方药（℞-only）;
药物动力学数据
药物代谢	deacetylation?
识别信息
	IUPAC命名法 1-Azabicyclo[2.2.2]oct-3-yl acetate; 3-Quinuclidinyl Acetate; ;
CAS号	827-61-2
PubChem CID	1979;
ChemSpider	1902 ;
UNII	0578K3ELIO;
KEGG	D02750 ;
ChEMBL	ChEMBL20835 ;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID2045658 ;
ECHA InfoCard	100.011.431
化学信息
化学式	C9H15NO2
摩尔质量	169.22 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES O=C(OC2C1CCN(CC1)C2)C;
	InChI InChI=1S/C9H15NO2/c1-7(11)12-9-6-10-4-2-8(9)3-5-10/h8-9H,2-6H2,1H3 ; Key:WRJPSSPFHGNBMG-UHFFFAOYSA-N ;

乙酰克里定或醋克利定是一种有机化合物，化学式为C₉H₁₅NO₂。它可由3-喹核醇（德语：3-Chinuclidinol）和乙酸酐反应制得。^[1]它和3-溴溴苄反应，得到季铵盐N-(3-溴苄基)乙酰克里定溴化物。^[2]

参考文献

^ M. H. Shaw, V. W. Shurtleff, J. A. Terrett, J. D. Cuthbertson, D. W. C. MacMillan. Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles. Science. 2016-06-10, 352 (6291): 1304–1308 [2021-08-15]. ISSN 0036-8075. PMC 5114852 . PMID 27127237. doi:10.1126/science.aaf6635 （英语）.
^ Primozic, Ines; Bolant, Marijana; Ramic, Alma; Tomic, Srdanka. Preparation of novel meta and para substituted N-benzyl protected quinuclidine esters and their resolution with butyrylcholinesterase. International Electronic Conference on Synthetic Organic Chemistry, 15th, Nov. 1-30, 2011. ISBN 3-906980-25-1.