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乙酰克里定

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乙酰克里定
Skeletal formula of aceclidine
Ball-and-stick model of the aceclidine molecule
临床资料
AHFS/Drugs.com国际药品名称
给药途径Topical (ophthalmic solution)
ATC码
法律规范状态
法律规范
  • 处方药(-only)
药物动力学数据
药物代谢deacetylation?
识别信息
  • 1-Azabicyclo[2.2.2]oct-3-yl acetate; 3-Quinuclidinyl Acetate
CAS号827-61-2  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.011.431 编辑维基数据链接
化学信息
化学式C9H15NO2
摩尔质量169.22 g·mol−1
3D模型(JSmol英语JSmol
  • O=C(OC2C1CCN(CC1)C2)C
  • InChI=1S/C9H15NO2/c1-7(11)12-9-6-10-4-2-8(9)3-5-10/h8-9H,2-6H2,1H3 checkY
  • Key:WRJPSSPFHGNBMG-UHFFFAOYSA-N checkY

乙酰克里定醋克利定是一种有机化合物,化学式为C9H15NO2。它可由3-喹核醇德语3-Chinuclidinol乙酸酐反应制得。[1]它和3-溴溴苄反应,得到季铵盐N-(3-溴苄基)乙酰克里定溴化物。[2]

参考文献

[编辑]
  1. ^ M. H. Shaw, V. W. Shurtleff, J. A. Terrett, J. D. Cuthbertson, D. W. C. MacMillan. Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles. Science. 2016-06-10, 352 (6291): 1304–1308 [2021-08-15]. ISSN 0036-8075. PMC 5114852可免费查阅. PMID 27127237. doi:10.1126/science.aaf6635 (英语). 
  2. ^ Primozic, Ines; Bolant, Marijana; Ramic, Alma; Tomic, Srdanka. Preparation of novel meta and para substituted N-benzyl protected quinuclidine esters and their resolution with butyrylcholinesterase. International Electronic Conference on Synthetic Organic Chemistry, 15th, Nov. 1-30, 2011. ISBN 3-906980-25-1.