尿激酶受体
外观
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尿激酶受体(英语:Urokinase receptor,或称为尿纤溶酶原激活物受体,缩写uPAR,也称为CD87,Cluster of Differentiation 87,分化簇87)是一种多结构域糖蛋白,通过糖磷脂酰肌醇(GPI)锚定在细胞膜上,最初被鉴定为尿激酶(尿纤溶酶原激活物,uPA)在细胞表面的饱和结合位点。uPAR在多种癌细胞表明都有发现[5]。
参考文献
[编辑]- ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000011422 - Ensembl, May 2017
- ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000046223 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Smith, HW; Marra, P; Marshall, CJ. uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.. The Journal of cell biology. 2008-08-25, 182 (4): 777–90. PMID 18725541. doi:10.1083/jcb.200712050.
外部链接
[编辑]- 医学主题词表(MeSH):PLAUR+protein,+human
- PDB中UniProt可用的所有结构信息之概述:Q03405 (Human Urokinase plasminogen activator surface receptor) 在PDBe-KB。
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