CD19

CD19
識別號
别名	CD19；, B4, CVID3, CD19 molecule
外部ID	OMIM：107265 MGI：88319 HomoloGene：1341 GeneCards：CD19
基因位置（人类）
染色体	16號染色體
终止	28,939,342 bp
基因位置（小鼠）
染色体	小鼠7号染色体
终止	126,014,061 bp
RNA表达模式
	查阅更多表达数据
基因本體
分子功能	• 血浆蛋白结合; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
細胞組分	• integral component of membrane; • 细胞膜; • integral component of plasma membrane; • 外排體; • 膜; • external side of plasma membrane; • 大分子复合体; • 脂筏模型;
生物學過程	• cellular defense response; • cell surface receptor signaling pathway; • regulation of immune response; • positive regulation of release of sequestered calcium ion into cytosol; • phosphatidylinositol phosphate biosynthetic process; • B cell receptor signaling pathway; • regulation of complement activation; • positive regulation of protein kinase B signaling; • B-1 B cell differentiation; • B cell proliferation involved in immune response; • immunoglobulin mediated immune response; • B cell mediated immunity; • positive regulation of phosphatidylinositol 3-kinase activity; • antigen receptor-mediated signaling pathway; • regulation of B cell receptor signaling pathway; • regulation of B cell activation; • adaptive immune response; • immune system process;
	Sources:Amigo / QuickGO
直系同源
	930
	12478
	ENSG00000177455
	ENSMUSG00000030724
	P15391
	P25918
	NM_001178098; NM_001770; NM_001385732
	NM_009844; NM_001357091
	NP_001171569; NP_001761
	NP_033974; NP_001344020
	維基數據
檢視/編輯人類	檢視/編輯小鼠

CD19（cluster of differentiation 19，分化簇19，也称为“B淋巴细胞抗原CD19”，B-lymphocyte antigen CD19，“B淋巴细胞表面抗原B4”，CVID3）是一种细胞表面蛋白质，由人类基因 CD19 编码，是B淋巴细胞的主要标志物^[5]^[6]。

参考文献[编辑]

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000177455 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000030724 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schroeder HW, Rich RR. Chapter 4: Antigen receptor genes, gene products, and co-receptors. Clinical immunology: Principles and Practice 4th. London. 2013: 47–51. ISBN 978-0-7234-3691-1. OCLC 823736017.
^ Scheuermann RH, Racila E. CD19 antigen in leukemia and lymphoma diagnosis and immunotherapy. Leukemia & Lymphoma. August 1995, 18 (5–6): 385–97. PMID 8528044. doi:10.3109/10428199509059636.

外部链接[编辑]

Mouse CD Antigen Chart
Human CD Antigen Chart
Human CD19 genome location and CD19 gene details page in the UCSC Genome Browser（英语：UCSC Genome Browser）.

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000177455 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000030724 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[Schroeder_2013-5] Schroeder HW, Rich RR. Chapter 4: Antigen receptor genes, gene products, and co-receptors. Clinical immunology: Principles and Practice 4th. London. 2013: 47–51. ISBN 978-0-7234-3691-1. OCLC 823736017.

[Scheuermann_1995-6] Scheuermann RH, Racila E. CD19 antigen in leukemia and lymphoma diagnosis and immunotherapy. Leukemia & Lymphoma. August 1995, 18 (5–6): 385–97. PMID 8528044. doi:10.3109/10428199509059636.

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