恩前列素
 | 此條目需要擴充。 (2014年5月3日) |
 | |
| 臨床資料 | |
|---|---|
| AHFS/Drugs.com | 国际药品名称 |
| ATC碼 | |
| 识别信息 | |
| |
| CAS号 | 73121-56-9  |
| PubChem CID | |
| UNII | |
| KEGG | |
| 化学信息 | |
| 化学式 | C23H28O6 |
| 摩尔质量 | 400.46 g/mol |
恩前列素是一種合成的類地諾前列酮前列腺素，它可以用來作胃部HCl分泌的強效抑制劑。[1] 因而常被用來作抗酸或潰瘍藥。它的藥理作用基本與米索前列醇相同。
參考文獻
[编辑]- ^ Roszkowski, AP; Garay, GL; Baker, S; Schuler, M; Carter, H. Gastric antisecretory and antiulcer properties of enprostil, (+/−)-11 alpha, 15 alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-9-oxoprosta-4,5,13(t)-trienoic acid methyl ester. The Journal of Pharmacology and Experimental Therapeutics. 1986, 239 (2): 382–9. PMID 3095537.
外部連結
[编辑]- Toshina, K.; Hirata, I.; Maemura, K.; Sasaki, S.; Murano, M.; Nitta, M.; Yamauchi, H.; Nishikawa, T.; Hamamoto, N.; Katsu, K. Enprostil, a Prostaglandin-E2 Analogue, Inhibits Interleukin-8 Production of Human Colonic Epithelial Cell Lines. Scandinavian Journal of Immunology. 2000, 52 (6): 570–5. PMID 11119262. doi:10.1046/j.1365-3083.2000.00815.x.
- Tari, Akira; Hamada, Masanori; Kamiyasu, Toshiki; Sumii, Koji; Haruma, Ken; Inoue, Masaki; Kishimoto, Shinya; Kajiyama, Goro; Walsh, John H. Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients. Digestive Diseases and Sciences. 1997, 42 (8): 1741–6. PMID 9286243. doi:10.1023/A:0000000000000.
- Ching, C. K.; Lam, S. K. A comparison of two prostaglandin analogues (enprostil vs misoprostol) in the treatment of acute duodenal ulcer disease. Journal of Gastroenterology. 1995, 30 (5): 607–14. PMID 8574332. doi:10.1007/BF02367786.