TLR4
外观
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Toll样受体4(英语:Toll-like receptor 4)是由人类基因 TLR4 编码的蛋白质,是一种膜蛋白质,也被称为CD284(分化簇284,cluster of differentiation 284),是模式识别受体中Toll样受体(TLR)家族的成员,可结合其配体脂多糖(LPS)激活NF-κB信号通路,在先天免疫系统中起到重要作用[6]。
参考文献
[编辑]- ^ 對toll like receptor 4起作用的藥物;在維基數據上查看/編輯參考.
- ^ 2.0 2.1 2.2 GRCh38: Ensembl release 89: ENSG00000136869 - Ensembl, May 2017
- ^ 3.0 3.1 3.2 GRCm38: Ensembl release 89: ENSMUSG00000039005 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Vaure C, Liu Y. A comparative review of toll-like receptor 4 expression and functionality in different animal species. Frontiers in Immunology. 2014-07-10, 5: 316. PMC 4090903
. PMID 25071777. doi:10.3389/fimmu.2014.00316.
外部链接
[编辑]- 医学主题词表(MeSH):Toll-Like+Receptor+4
- PDB中UniProt可用的所有结构信息之概述:O00206 (Toll-like receptor 4) 在PDBe-KB。
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