CD6

CD6
已知的結構
PDB	直系同源搜尋: PDBe RCSB
PDBID列表
	5A2E
識別號
別名	CD6；, TP120, CD6 molecule
外部ID	OMIM：186720 MGI：103566 HomoloGene：4893 GeneCards：CD6
相關疾病
	多發性硬化症
基因位置（人類）
染色體	11號染色體
終止	61,020,377 bp
基因位置（小鼠）
染色體	小鼠19號染色體
終止	10,807,422 bp
基因本體
分子功能	• lipopolysaccharide binding; • lipoteichoic acid binding; • scavenger receptor activity; • 血漿蛋白結合; • 相同蛋白質結合;
細胞組分	• integral component of membrane; • 膜; • intrinsic component of plasma membrane; • 細胞膜; • integral component of plasma membrane; • T cell receptor complex; • 細胞外區域; • 免疫突觸; • external side of plasma membrane;
生物學過程	• positive regulation of cytokine production involved in inflammatory response; • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; • adaptive immune response; • immune system process; • acute inflammatory response to antigenic stimulus; • 受體介導的內吞作用; • response to lipopolysaccharide; • 細胞粘附; • positive regulation of T cell proliferation; • 先天免疫系統; • immunological synapse formation; • lipopolysaccharide-mediated signaling pathway; • vesicle-mediated transport; • 內吞作用;
	Sources:Amigo / QuickGO
直系同源
	923
	12511
	ENSG00000013725
	ENSMUSG00000024670
	P30203
	Q61003
	NM_001254750; NM_001254751; NM_006725
	NM_001037801; NM_009852
	NP_001241679; NP_001241680; NP_006716
	NP_001032890; NP_033982
	維基數據
檢視/編輯人類	檢視/編輯小鼠

CD6（cluster of differentiation 6，分化簇6）是一種細胞表面蛋白質，由人類基因 CD6 編碼^[6]，主要在T淋巴細胞等免疫細胞上表達^[7]。

參考文獻[編輯]

^ 與CD6相關的疾病；在維基數據上查看/編輯參考.
^ ^2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000013725 - Ensembl, May 2017
^ ^3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000024670 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Entrez Gene: CD6 CD6 molecule.
^ Bowen MA, Patel DD, Li X, Modrell B, Malacko AR, Wang WC, Marquardt H, Neubauer M, Pesando JM, Francke U. Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J. Exp. Med. 1995, 181 (6): 2213–20. PMC 2192054 . PMID 7760007. doi:10.1084/jem.181.6.2213.

外部連結[編輯]

醫學主題詞表（MeSH）：CD6+protein,+human
Human CD6 genome location and CD6 gene details page in the UCSC Genome Browser（英語：UCSC Genome Browser）.
PDB中UniProt可用的所有結構資訊之概述：P30203 (Human T-cell differentiation antigen CD6) 在PDBe-KB（英語：PDBe-KB）。

CD6引用了美國國家醫學圖書館提供的數據，這些數據屬於公共領域。

[1] 與CD6相關的疾病；在維基數據上查看/編輯參考.

[refGRCh38Ensembl-2] 2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000013725 - Ensembl, May 2017

[refGRCm38Ensembl-3] 3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000024670 - Ensembl, May 2017

[4] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-6] Entrez Gene: CD6 CD6 molecule.

[pmid7760007-7] Bowen MA, Patel DD, Li X, Modrell B, Malacko AR, Wang WC, Marquardt H, Neubauer M, Pesando JM, Francke U. Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J. Exp. Med. 1995, 181 (6): 2213–20. PMC 2192054 . PMID 7760007. doi:10.1084/jem.181.6.2213.

[1]

[2]

[3]

[4]

[5]

[6]

[7]