庚酸雄甾醇酮

**庚酸雄甾醇酮**
臨床資料
商品名（英語：Drug nomenclature）	Anaboleen Depot
其他名稱	Stanolone enanthate; Dihydrotestosterone enanthate; DHT enanthate; Dihydrotestosterone heptanoate; DHTH; 5α-Androstan-17β-ol-3-one 17β-heptanoate
給藥途徑	Intramuscular injection
藥物類別（英語：Drug class）	Androgen; Anabolic steroid; Androgen ester
識別資訊
	IUPAC命名法 [(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] heptanoate; ;
CAS號	33776-88-4
PubChem CID	160230;
ChemSpider	140831;
UNII	UAQ3N36A25;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID90955358 ;
化學資訊
化學式	C26H42O3
摩爾質量	402.62 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES CCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C;
	InChI InChI=1S/C26H42O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h18,20-23H,4-17H2,1-3H3/t18-,20-,21-,22-,23-,25-,26-/m0/s1; Key:DDYHAKNCTGGYOK-LVYWIKMTSA-N;

庚酸雄甾醇酮（英語：Androstanolone enanthate），也稱為庚酸雄諾龍或庚酸二氫睾酮，是一種合成的雄激素和合成代謝類固醇和二氫睾酮酯。^[1]^[2]它用作注射劑，並作為雄甾醇酮（二氫睾酮）的前體藥物。該藥物已被研究並發現可有效治療男孩和成年男性的男性乳房發育症。^[3]^[4]^[5]已對庚酸雄甾醇酮的藥理學進行了研究。^[6]^[7]

參見[編輯]

雄激素酯列表

參考資料[編輯]

^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 640–. ISBN 978-1-4757-2085-3.
^ I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 261–. ISBN 978-94-011-4439-1.
^ Swerdloff, Ronald S.; Wang, Christina. Dihydrotestosterone: A rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillière's Clinical Endocrinology and Metabolism. 1998, 12 (3): 501–506. ISSN 0950-351X. PMID 10332569. doi:10.1016/S0950-351X(98)80267-X.
^ Eberle AJ, Sparrow JT, Keenan BS. Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. J. Pediatr. 1986, 109 (1): 144–9. PMID 3088241. doi:10.1016/s0022-3476(86)80596-0.
^ Swerdloff, Ronald S.; Dudley, Robert E.; Page, Stephanie T.; Wang, Christina; Salameh, Wael A. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. 2017, 38 (3): 220–254. ISSN 0163-769X. PMC 6459338 . PMID 28472278. doi:10.1210/er.2016-1067 .
^ Keenan, Bruce S.; Eberle, Andrea J.; Sparrow, James T.; Greger, Nancy G.; Panko, Walter B. Dihydrotestosterone Heptanoate: Synthesis, Pharmacokinetics, and Effects on Hypothalamic-Pituitary-Testicular Function. The Journal of Clinical Endocrinology & Metabolism. 1987, 64 (3): 557–562. ISSN 0021-972X. PMID 3546348. doi:10.1210/jcem-64-3-557.
^ Coutts SB, Kicman AT, Hurst DT, Cowan DA. Intramuscular administration of 5 alpha-dihydrotestosterone heptanoate: changes in urinary hormone profile. Clin. Chem. November 1997, 43 (11): 2091–8. PMID 9365393. doi:10.1093/clinchem/43.11.2091 .

[Elks2014-1] J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 640–. ISBN 978-1-4757-2085-3.

[MortonHall2012-2] I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 261–. ISBN 978-94-011-4439-1.

[SwerdloffWang1998-3] Swerdloff, Ronald S.; Wang, Christina. Dihydrotestosterone: A rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillière's Clinical Endocrinology and Metabolism. 1998, 12 (3): 501–506. ISSN 0950-351X. PMID 10332569. doi:10.1016/S0950-351X(98)80267-X.

[pmid3088241-4] Eberle AJ, Sparrow JT, Keenan BS. Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. J. Pediatr. 1986, 109 (1): 144–9. PMID 3088241. doi:10.1016/s0022-3476(86)80596-0.

[SwerdloffDudley2017-5] Swerdloff, Ronald S.; Dudley, Robert E.; Page, Stephanie T.; Wang, Christina; Salameh, Wael A. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. 2017, 38 (3): 220–254. ISSN 0163-769X. PMC 6459338 . PMID 28472278. doi:10.1210/er.2016-1067 .

[KeenanEberle1987-6] Keenan, Bruce S.; Eberle, Andrea J.; Sparrow, James T.; Greger, Nancy G.; Panko, Walter B. Dihydrotestosterone Heptanoate: Synthesis, Pharmacokinetics, and Effects on Hypothalamic-Pituitary-Testicular Function. The Journal of Clinical Endocrinology & Metabolism. 1987, 64 (3): 557–562. ISSN 0021-972X. PMID 3546348. doi:10.1210/jcem-64-3-557.

[pmid9365393-7] Coutts SB, Kicman AT, Hurst DT, Cowan DA. Intramuscular administration of 5 alpha-dihydrotestosterone heptanoate: changes in urinary hormone profile. Clin. Chem. November 1997, 43 (11): 2091–8. PMID 9365393. doi:10.1093/clinchem/43.11.2091 .

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