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齐洛呋胺

维基百科,自由的百科全书
齐洛呋胺
臨床資料
ATC碼
  • 未分配
识别信息
  • (1R)-N-Ethyl-2-phenyl-1-[(2R)-tetrahydrofuran-2-yl]ethanamine
CAS号3563-92-6
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C14H21NO
摩尔质量219.33 g·mol−1
3D模型(JSmol英语JSmol
  • O2[C@@H]([C@H](NCC)Cc1ccccc1)CCC2
  • InChI=1S/C14H21NO/c1-2-15-13(14-9-6-10-16-14)11-12-7-4-3-5-8-12/h3-5,7-8,13-15H,2,6,9-11H2,1H3/t13-,14-/m1/s1 checkY
  • Key:DOFCLOLKFGSRTG-ZIAGYGMSSA-N checkY

齐洛呋胺英语:Zylofuramine[1])是一种兴奋剂药物。它于1961年开发,[2][3]旨在用作抑制食欲和治疗老年人的老年痴呆症,但有关它的信息很少,而且似乎从未上市过。[4]

化学结构与其他N-乙基取代兴奋剂药物如乙基苯丙胺苯基乙基胺己酮具有相似性。

参考资料

[编辑]
  1. ^ US patent 3091621,Clarke RL,「Alpha-Aryl or Aralkyl Tetrahydrofurfurylamines」,发行于1963-05-28,指定于Sterling Drugs 
  2. ^ Clarke RL, Harris LS. α-Benzyltetrahydrofurfurylamines -- A New Series of Psychomotor Stimulants. I. Journal of Medicinal and Pharmaceutical Chemistry. January 1962, 5 (1): 77–95. PMID 14046619. doi:10.1021/jm01236a010. 
  3. ^ Clarke RL, Tullar BF, Harris LS. α-Benzyltetrahydrofurfurylamines -- A New Series of Psychomotor Stimulants. II. Resolution of Isomers. Journal of Medicinal and Pharmaceutical Chemistry. March 1962, 5 (2): 362–72. PMID 14051912. doi:10.1021/jm01237a014. 
  4. ^ Harris LS, Clarke RL, Dembinski JR. α-Benzyltetrahydrofurfurylamines -- A New Series of Psychomotor Stimulants. III. The Pharmacology of D-Threo α-Benzyl-N-Ethyltetrahydrofurfurylamine (Zylofuramine). Archives Internationales de Pharmacodynamie et de Therapie. December 1963, 146: 392–405. PMID 14099588.