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庚酸睾酮

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庚酸睾酮
临床资料
商品名英语Drug nomenclatureDelatestryl, Xyosted, others
其他名称TE; Testosterone heptanoate; Testosterone 17β-heptanoate; NSC-17591
给药途径Intramuscular injection, subcutaneous injection
药物类别英语Drug classAndrogen; Anabolic steroid; Androgen ester
法律规范状态
法律规范
药物动力学数据
生物利用度Oral: very low
Intramuscular: high
药物代谢Liver
生物半衰期Intramuscular: 4–5 days
排泄途径Urine
识别信息
  • [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate
CAS号315-37-7
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.005.686 编辑维基数据链接
化学信息
化学式C26H40O3
摩尔质量400.60 g·mol−1
3D模型(JSmol英语JSmol
  • CCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
  • InChI=1S/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/m0/s1
  • Key:VOCBWIIFXDYGNZ-IXKNJLPQSA-N

庚酸睾酮(英语:Testosterone enanthate或 Testosterone heptanoate,也称作雄-4-烯-17β-醇-3-酮-17β-庚酸酯androst-4-en-17β-ol-3-one 17β-heptanoate,商品名 Delatestryl 或 Xyosted)是一种合成雄激素药物,是睾酮17号C原子β羟基与正庚酸酯化的产物,化学式C26H40O3,用于治疗人性腺功能低下症[1][2][3]

参考文献

[编辑]
  1. ^ Nieschlag E, Behre HM, Nieschlag S. Testosterone: Action, Deficiency, Substitution. Cambridge University Press. 26 July 2012: 315– [2022-03-07]. ISBN 978-1-107-01290-5. (原始内容存档于2022-04-07). 
  2. ^ Nieschlag E, Behre HM, Nieschlag S. Andrology: Male Reproductive Health and Dysfunction. Springer Science & Business Media. 13 January 2010: 442– [2022-03-07]. ISBN 978-3-540-78355-8. (原始内容存档于2019-04-14). 
  3. ^ Llewellyn W. Anabolics. Molecular Nutrition Llc. 2011: 208–211 [2022-03-07]. ISBN 978-0-9828280-1-4. (原始内容存档于2022-03-11).