RTS,S

**RTS,S**
疫苗说明
目標	惡性瘧原蟲;較小程度的B型肝炎
种类	蛋白质亚基疫苗
臨床資料
商品名（英语：Drug nomenclature）	Mosquirix
给药途径	肌肉注射 (0.5 毫升)
法律規範狀態
法律規範	处方药（℞-only）;
识别信息
CAS号	149121-47-1

RTS,S/AS01 (商業名稱為Mosquirix)是一種基於重組蛋白的瘧疾疫苗。它是唯一獲得批准並廣泛使用的瘧疾疫苗。截至2022年4月 (2022-04)^[update]，該疫苗已為生活在中度至高度瘧疾傳播地區的100萬名兒童接種，隨著疫苗生產的擴大，還將提供數百萬劑^[3]^[4]。2歲前的嬰兒至少需接種三劑，第四劑可將保護再延長1至2年^[3]。該疫苗使嚴重瘧疾住院的人數減少了約30%^[3]。

參考資料[编辑]

^ Mosquirix H-W-2300. European Medicines Agency (EMA). [4 March 2021]. （原始内容存档于2019-11-23）.
^ RTS,S Malaria Vaccine: 2019 Partnership Award Honoree. YouTube. Global Health Technologies Coalition. [6 October 2021].
^ ^3.0 ^3.1 ^3.2 First malaria vaccine hits 1 million dose milestone — although it has its shortcomings. NPR. 13 May 2022 [2 January 2023]. （原始内容存档于2022-11-13）.
^ Millions more children to benefit from malaria vaccine as UNICEF secures supply. UNICEF. 16 August 2022 [2 January 2023]. （原始内容存档于2023-01-02）（英语）.

延伸閱讀[编辑]

Asante KP, Abdulla S, Agnandji S, Lyimo J, Vekemans J, Soulanoudjingar S, et al. Safety and efficacy of the RTS,S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial. The Lancet. Infectious Diseases. October 2011, 11 (10): 741–9. PMID 21782519. doi:10.1016/S1473-3099(11)70100-1.
Wilby KJ, Lau TT, Gilchrist SE, Ensom MH. Mosquirix (RTS,S): a novel vaccine for the prevention of Plasmodium falciparum malaria. The Annals of Pharmacotherapy. March 2012, 46 (3): 384–93 [2023-04-21]. PMID 22408046. S2CID 32412123. doi:10.1345/aph.1AQ634. （原始内容存档于2021-10-27）.

外部連結[编辑]

Mosquirix: Product information （页面存档备份，存于互联网档案馆）
Mosquirix: Public Assessment Report （页面存档备份，存于互联网档案馆）

[ema-1] Mosquirix H-W-2300. European Medicines Agency (EMA). [4 March 2021]. （原始内容存档于2019-11-23）.

[2] RTS,S Malaria Vaccine: 2019 Partnership Award Honoree. YouTube. Global Health Technologies Coalition. [6 October 2021].

[npr-052022-3] 3.0 ^3.1 ^3.2 First malaria vaccine hits 1 million dose milestone — although it has its shortcomings. NPR. 13 May 2022 [2 January 2023]. （原始内容存档于2022-11-13）.

[unicef-082022-4] Millions more children to benefit from malaria vaccine as UNICEF secures supply. UNICEF. 16 August 2022 [2 January 2023]. （原始内容存档于2023-01-02）（英语）.

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