甲苯米定

甲苯米定
临床资料
ATC码	未分配;
识别信息
	IUPAC命名法 N'-[2-(3-methoxyphenoxy)propyl]-2-(3-methylphenyl)ethanimidamide; ;
CAS号	6443-50-1
PubChem CID	22951;
ChemSpider	21486 ;
UNII	NY0PC84NZK;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID90863843 ;
化学信息
化学式	C19H24N2O2
摩尔质量	312.41 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CC1=CC(=CC=C1)CC(=NCC(C)OC2=CC=CC(=C2)OC)N;
	InChI InChI=1S/C19H24N2O2/c1-14-6-4-7-16(10-14)11-19(20)21-13-15(2)23-18-9-5-8-17(12-18)22-3/h4-10,12,15H,11,13H2,1-3H3,(H2,20,21) ; Key:JRYTUFKIORWTNI-UHFFFAOYSA-N ;

甲苯米定（英语：Xylamidine）是一种含氮有机化合物，分子式C₁₉H₂₄N₂O₂，属于5-HT_1A 受体拮抗剂，无法通过血脑屏障^[1]^[2]。它可以3-甲氧基苯酚为原料经多步反应合成得到。^[3]

参考文献

^ Fuller RW, Kurz KD, Mason NR, Cohen ML. Antagonism of a peripheral vascular but not an apparently central serotonergic response by xylamidine and BW 501C67. European Journal of Pharmacology. June 1986, 125 (1): 71–7. PMID 3732393. doi:10.1016/0014-2999(86)90084-1.
^ Dedeoğlu A, Fisher LA. Central and peripheral injections of the 5-HT2 agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, modify cardiovascular function through different mechanisms. The Journal of Pharmacology and Experimental Therapeutics. December 1991, 259 (3): 1027–34. PMID 1762059.
^ The Wellcome Foundation. Werkwijze voor het bereiden van amidinen of daarvan afgeleide zuur-additiezouten, die werkzaam zijn als antagonisten van 5-hydroxytryptamine, en van farmaceutische preparaten, die ten minste een van deze verbindingen als werkzame verbinding bevatten（荷兰文）, 1965. NL6508754A.