过氧化物酶体增殖物活化受体γ
维基百科，自由的百科全书
过氧化物酶体增殖物活化受体γ（Peroxisome proliferator-activated receptor gamma ，缩写为PPAR-γ或PPARG），也称胰島素增敏劑受体（glitazone receptor），或 NR1C3（意为核受体第一亚科C集团第3号，nuclear receptor subfamily 1, group C, member 3）是一种位于人类染色体上的二型核受体，由PPARG基因编码。[1][2][3]对脂肪细胞和胰岛素有重要的作用，是治疗糖尿病的研究对象之一。[4]
来源 [编辑]
- ^ Greene ME, Blumberg B, McBride OW, Yi HF, Kronquist K, Kwan K, Hsieh L, Greene G, Nimer SD. Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expr. 1995, 4 (4-5): 281–99. PMID 7787419.
- ^ Elbrecht A, Chen Y, Cullinan CA, Hayes N, Leibowitz M, Moller DE, Berger J. Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2. Biochem. Biophys. Res. Commun. 1996.July, 224 (2): 431–7. doi:10.1006/bbrc.1996.1044. PMID 8702406.
- ^ Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, Grimaldi PA, Kadowaki T, Lazar MA, O'Rahilly S, Palmer CN, Plutzky J, Reddy JK, Spiegelman BM, Staels B, Wahli W. International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol. Rev. 2006.December, 58 (4): 726–41. doi:10.1124/pr.58.4.5. PMID 17132851.
- ^ 刘英姿 ,刘昭前 , 周宏灏. 过氧化物酶体增殖物激活受体γ激动剂和拮抗剂研究进展. 中国临床药理学杂志. 2007, 23 (4): 308–310. 1001-6821(2007)04-0308-03 （中文）.
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
