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布马佐辛

维基百科,自由的百科全书
布马佐辛
臨床資料
给药途径Oral
ATC碼
  • 未分配
识别信息
  • 6-ethyl- 3-[(1-hydroxycyclopropyl)methyl]- 11,11-dimethyl- 1,2,3,4,5,6-hexahydro- 2,6-methano- 3-benzazocin-8- ol
    or
    2-(1-hydroxy- cyclopropylmethyl)- 5-ethyl- 9,9-dimethyl- 2'-hydroxy- 6,7-benzomorphan
CAS号83829-76-9  checkY
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C20H29NO2
摩尔质量315.46 g·mol−1
3D模型(JSmol英语JSmol
  • OC1(CC1)CN4[C@@H]3Cc2c(cc(O)cc2)[C@@](C3(C)C)(CC4)CC

布马佐辛INN:bremazocine)是一种含氮有机化合物,分子式C20H29NO2,属喷他佐辛结构类似物,可作为镇痛药利尿劑[1],1984年确定其化学结构[2]

参考文献

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  1. ^ Dortch-Carnes J, Potter DE. Bremazocine: a kappa-opioid agonist with potent analgesic and other pharmacologic properties. CNS Drug Reviews. 2005, 11 (2): 195–212. PMC 6741727可免费查阅. PMID 16007240. doi:10.1111/j.1527-3458.2005.tb00270.x. 
  2. ^ Verlinde CL, Blaton NM, De Ranter CJ, Peeters OM. 5-Ethyl-2'-hydroxy-2-[(1-hydroxycyclopropyl) methyl]-9, 9-dimethyl-6, 7-benzomorphan hydrochloride (bremazocine), C20H29NO2. HCl. Acta Crystallogr. C. 1984, 40 (10): 1759–1761. Bibcode:1984AcCrC..40.1759V. doi:10.1107/S0108270184009434. 

外部链接

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