孕三烯酮
外观
临床资料 | |
---|---|
商品名 | Dimetriose, Dimetrose, Nemestran, others |
其他名称 | Ethylnorgestrienone; A-46745; R2323; R-2323; RU-2323; 17α-Ethynyl-18-methyl-δ9,11-19-nortestosterone; 17α-Ethynyl-18-methylestra-4,9,11-trien-17β-ol-3-one; 13β-Ethyl-18,19-dinor-17α-pregna-4,9,11-trien-20-yn-17β-ol-3-one |
AHFS/Drugs.com | 国际药品名称 |
怀孕分级 |
|
给药途径 | By mouth, vaginal[1] |
药物类别 | Progestin; Progestogen; Antiprogestogen; Androgen; Anabolic steroid; Steroidogenesis inhibitor; Antiestrogen |
ATC码 | |
药物动力学数据 | |
血浆蛋白结合率 | To albumin[1] |
药物代谢 | Liver (hydroxylation)[1] |
生物半衰期 | 27.3 hours[1] |
排泄途径 | Urine and bile[1] |
识别信息 | |
| |
CAS号 | 16320-04-0 |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.210.606 |
化学信息 | |
化学式 | C21H24O2 |
摩尔质量 | 308.41 g/mol |
3D模型(JSmol) | |
| |
|
孕三烯酮(英语:Gestrinone)是一种用于治疗子宫内膜异位症的药物[2][3],也用于治疗子宫肌瘤、经血过多以及进行生育控制[1]。孕三烯酮通常单独使用,不与其他药物联合使用[4],可由口服给药或阴道内给药[1]。
参考文献
[编辑]- ^ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Eric J. Thomas; John Rock. Modern Approaches to Endometriosis. Springer Science & Business Media. 6 December 2012: 228, 232, 234. ISBN 978-94-011-3864-2.
- ^ Coutinho EM. Therapeutic experience with gestrinone. Prog. Clin. Biol. Res. 1990, 323: 233–40. PMID 2406749.
- ^ Dr. Ian Morton; I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999: 132–. ISBN 978-0-7514-0499-9.
- ^ 引用错误:没有为名为
Drugs.com
的参考文献提供内容
延伸阅读
[编辑]- Coutinho E, Gonçalves MT, Azadian-Boulanger G, Silva AR. Endometriosis therapy with gestrinone by oral, vaginal or parenteral administration. Contrib Gynecol Obstet. 1987, 16: 227–35. PMID 3691096. doi:10.1159/000414891 (不活跃 2018-10-13).
- Coutinho EM. Therapeutic experience with gestrinone. Prog. Clin. Biol. Res. 1990, 323: 233–40. PMID 2406749.