孕三烯酮
外觀
臨床資料 | |
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商品名 | Dimetriose, Dimetrose, Nemestran, others |
其他名稱 | Ethylnorgestrienone; A-46745; R2323; R-2323; RU-2323; 17α-Ethynyl-18-methyl-δ9,11-19-nortestosterone; 17α-Ethynyl-18-methylestra-4,9,11-trien-17β-ol-3-one; 13β-Ethyl-18,19-dinor-17α-pregna-4,9,11-trien-20-yn-17β-ol-3-one |
AHFS/Drugs.com | 國際藥品名稱 |
懷孕分級 |
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給藥途徑 | By mouth, vaginal[1] |
藥物類別 | Progestin; Progestogen; Antiprogestogen; Androgen; Anabolic steroid; Steroidogenesis inhibitor; Antiestrogen |
ATC碼 | |
藥物動力學數據 | |
血漿蛋白結合率 | To albumin[1] |
藥物代謝 | Liver (hydroxylation)[1] |
生物半衰期 | 27.3 hours[1] |
排泄途徑 | Urine and bile[1] |
識別資訊 | |
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CAS號 | 16320-04-0 |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.210.606 |
化學資訊 | |
化學式 | C21H24O2 |
摩爾質量 | 308.41 g/mol |
3D模型(JSmol) | |
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孕三烯酮(英語:Gestrinone)是一種用於治療子宮內膜異位症的藥物[2][3],也用於治療子宮肌瘤、經血過多以及進行生育控制[1]。孕三烯酮通常單獨使用,不與其他藥物聯合使用[4],可由口服給藥或陰道內給藥[1]。
參考文獻
[編輯]- ^ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Eric J. Thomas; John Rock. Modern Approaches to Endometriosis. Springer Science & Business Media. 6 December 2012: 228, 232, 234. ISBN 978-94-011-3864-2.
- ^ Coutinho EM. Therapeutic experience with gestrinone. Prog. Clin. Biol. Res. 1990, 323: 233–40. PMID 2406749.
- ^ Dr. Ian Morton; I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999: 132–. ISBN 978-0-7514-0499-9.
- ^ 引用錯誤:沒有為名為
Drugs.com
的參考文獻提供內容
延伸閱讀
[編輯]- Coutinho E, Gonçalves MT, Azadian-Boulanger G, Silva AR. Endometriosis therapy with gestrinone by oral, vaginal or parenteral administration. Contrib Gynecol Obstet. 1987, 16: 227–35. PMID 3691096. doi:10.1159/000414891 (不活躍 2018-10-13).
- Coutinho EM. Therapeutic experience with gestrinone. Prog. Clin. Biol. Res. 1990, 323: 233–40. PMID 2406749.