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5-氯-α-甲基色胺

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5-氯-α-甲基色胺
臨床資料
ATC碼
  • 未分配
法律規範狀態
法律規範
  • PSA
  • 在新加坡非法
识别信息
  • 1-(5-Chloro-1H-indol-3-yl)propan-2-amine
CAS号712-07-2  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C11H13ClN2
摩尔质量208.69 g·mol−1
3D模型(JSmol英语JSmol
  • CC(Cc1c[nH]c2c1cc(cc2)Cl)N
  • InChI=1S/C11H13ClN2/c1-7(13)4-8-6-14-11-3-2-9(12)5-10(8)11/h2-3,5-7,14H,4,13H2,1H3
  • Key:QMKOQSCXSYPIPB-UHFFFAOYSA-N

5-氯-α-甲基色胺(5-氯-αMT,PAL-542)是一种与α-甲基色胺英语Alpha-Methyltryptamine(αMT)相关的色胺衍生物,也是少数已知的特定血清素-多巴胺释放剂英语Serotonin–dopamine_releasing_agent(SDRA) 之一。[1][2]在动物研究中,它被发现可用于治疗可卡因依赖英语cocaine dependence[2]它可以5-氯吲哚-3-甲醛为原料制得。[3]它在新加坡非法。[4]

参考文献

[编辑]
  1. ^ Blough BE, Landavazo A, Partilla JS, et al. Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorganic & Medicinal Chemistry Letters. October 2014, 24 (19): 4754–8. PMC 4211607可免费查阅. PMID 25193229. doi:10.1016/j.bmcl.2014.07.062. 
  2. ^ 2.0 2.1 Banks ML, Bauer CT, Blough BE, et al. Abuse-related effects of dual dopamine/serotonin releasers with varying potency to release norepinephrine in male rats and rhesus monkeys. Exp Clin Psychopharmacol. June 2014, 22 (3): 274–84. PMC 4067459可免费查阅. PMID 24796848. doi:10.1037/a0036595. 
  3. ^ Bruce E. Blough, Antonio Landavazo, John S. Partilla, Ann M. Decker, Kevin M. Page, Michael H. Baumann, Richard B. Rothman. Alpha-ethyltryptamines as dual dopamine–serotonin releasers. Bioorganic & Medicinal Chemistry Letters. 2014-10, 24 (19): 4754–4758 [2021-10-20]. PMC 4211607可免费查阅. PMID 25193229. doi:10.1016/j.bmcl.2014.07.062. (原始内容存档于2020-09-18) (英语). 
  4. ^ Misuse of Drugs Act - Singapore Statutes Online. sso.agc.gov.sg. [2021-10-20]. (原始内容存档于2021-04-17). 

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