依他佐辛
外观
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臨床資料 | |
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给药途径 | Oral |
ATC碼 |
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法律規範狀態 | |
法律規範 |
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识别信息 | |
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CAS号 | 72522-13-5( 72150-17-5 (bromide)) |
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CompTox Dashboard (EPA) | |
化学信息 | |
化学式 | C15H21NO |
摩尔质量 | 231.34 g·mol−1 |
3D模型(JSmol) | |
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依他佐辛(英語:Eptazocine,商品名:Sedapain)是一种含氮有机化合物,化学式C15H21NO,属于苯吗喃衍生物,可作为類阿片镇痛药[1][2][3][4]。常以氢溴酸盐的形式给药,用于癌症和术后患者镇痛。由日本医药工业株式会社开发,1987年获批上市[5]。
参考文献
[编辑]- ^ Index nominum 2000: international drug directory. Taylor & Francis US. 2000: 396 [29 November 2011]. ISBN 978-3-88763-075-1.
- ^ American Chemical Society. Division of Medicinal Chemistry. Cumulative NCE Introduction index, 1983-189, by Indication. Bristol JA (编). Annual Reports in Medicinal Chemistry. Academic Press. 1990: 381 [29 November 2011]. ISBN 978-0-12-040525-1.
- ^ Nabeshima T, Matsuno K, Kamei H, Kameyama T. The interaction of eptazocine, a novel analgesic, with opioid receptors. Research Communications in Chemical Pathology and Pharmacology. May 1985, 48 (2): 173–181. PMID 2992058.
- ^ Nagase H, Fujii H. Synthesis of Novel Basic Skeletons Derived from Naltrexone. Nagase H, Calderon SN (编). Chemistry of Opioids. Springer. 21 January 2011: 280 [29 November 2011]. ISBN 978-3-642-18106-1.
- ^ 张泓. 介绍新药—Eptazocine Hydrobromide. 中国药理学通报. 1989, (5): 302.
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