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β1肾上腺素受体激动药

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β1肾上腺素受体刺激剂(Beta1-adrenergic agonists)又名为 β1肾上腺素受体激动剂,是一种能选择性作用于β1肾上腺素受体英语beta-1 adrenergic receptor激动剂,β1肾上腺素受体刺激剂主要作用于心脏,通常由正肾上腺素激活。正肾上腺素则主要由交感神经的肾上腺素和循环全身的肾上腺素释放而得。β1肾上腺素受体刺激剂激活后的效果主要为刺激心脏,例如:加速心率心肌收缩能力英语myocardial contractility心导速率英语conduction velocity[1]

地诺帕明[2][3]多保他命扎莫特罗都属于β1肾上腺素受体刺激剂。

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  1. ^ Sakuma, Tsutomu; Hida, Mieko; Nambu, Yoshihiro; Osanai, Kazuhiro; Toga, Hirohisa; Takahashi, Keiji; Ohya, Nobuo; Inoue, Masao; Watanabe, Yoh. Beta1-Adrenergic Agonist Is a Potent Stimulator of Alveolar Fluid Clearance in Hyperoxic Rat Lungs.. The Japanese Journal of Pharmacology (Japanese Pharmacological Society). 2001, 85 (2): 161–166. ISSN 0021-5198. doi:10.1254/jjp.85.161. 
  2. ^ Sakuma T, Hida M, Nambu Y, et al. Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs. Jpn. J. Pharmacol. February 2001, 85 (2): 161–6. PMID 11286398. doi:10.1254/jjp.85.161. 
  3. ^ Nishio R, Matsumori A, Shioi T, et al. Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart. J. Am. Coll. Cardiol. September 1998, 32 (3): 808–15 [2018-05-11]. PMID 9741531. doi:10.1016/S0735-1097(98)00314-3. (原始内容存档于2019-09-09).